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meta|Evidence - COVID-19

Live meta-analysis and evidence synthesis of therapies for COVID19

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Our approach
     
button bars forest bayes pooled summary
Treament Trials
deathsclinical improvementdeath or ventilation
14 0.86 [0.78; 0.94], 5 RCTs, I2=0% demonstrated
moderate degree of certainty		 1.16 [0.84; 1.60], 2 RCTs, I2=0%
inconclusive result		 0.71 [0.37; 1.35], 1 RCT, I2=0%
inconclusive result
6 0.91 [0.79; 1.05], 5 RCTs, I2=0%
inconclusive result		 1.32 [1.16; 1.50], 4 RCTs, I2=0% demonstrated
moderate degree of certainty		 0.97 [0.85; 1.10], 1 RCT, I2=0%
inconclusive result
35 1.10 [0.99; 1.22], 10 RCTs, I2=0%
inconclusive result		 1.02 [0.73; 1.42], 1 RCT, I2=0%
inconclusive result		 1.14 [1.03; 1.25], 3 RCTs, I2=0%
statistically significant harm
17 0.79 [0.49; 1.29], 6 RCTs, I2=0%
inconclusive result		 0.99 [0.73; 1.33], 3 RCTs, I2=5%
inconclusive result		 0.67 [0.14; 3.26], 1 RCT, I2=0%
inconclusive result
8 1.15 [0.96; 1.38], 2 RCTs, I2=0%
inconclusive result		- 1.05 [0.90; 1.23], 1 RCT, I2=0%
inconclusive result
18 0.84 [0.66; 1.06], 6 RCTs, I2=0%
inconclusive result		 1.25 [1.02; 1.52], 4 RCTs, I2=48% demonstrated
moderate degree of certainty		 0.62 [0.42; 0.93], 3 RCTs, I2=0% demonstrated
moderate degree of certainty
6 0.51 [0.25; 1.07], 1 RCT, I2=0%
inconclusive result		 1.76 [1.12; 2.78], 1 RCT, I2=0% demonstrated
moderate degree of certainty		-
6 1.01 [0.91; 1.13], 3 RCTs, I2=0%
inconclusive result		 1.31 [0.94; 1.83], 1 RCT, I2=0%
inconclusive result		-
3 0.31 [0.04; 2.15], 2 RCTs, I2=0%
inconclusive result		--
6 0.65 [0.07; 5.74], 2 RCTs, I2=51%
inconclusive result		--
1 ---

Demonstrated: statistically demonstrated that is statistically significant with a strict control of overall risk of type 1 error; inconclusive: not nominally statistically significant; suggested: nominally statistically significant but without a strict control of overall risk of type 1 error

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N) and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

   

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