× We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click our cookies policy for information on how to change your cookie settings.

× Important note: Due to the end of funding, these reviews are no longer in living mode. We try to update them on a monthly basis.

meta|Evidence - COVID-19

Living meta-analysis and evidence synthesis of therapies for COVID19

Member of the meta|Evidence galaxy

tutorial video
En Fr

Our approach

RSS

button bars forest bayes pooled summary circles

Treament	Trials	auto
Treament	Trials	deaths	clinical improvement	death or ventilation
study description meta-analysis results	1	0.70 [0.50; 0.97], 1 RCT, I2=0% unassessable degree of certainty	1.08 [0.97; 1.20], 1 RCT, I2=0% inconclusive result	-
study description meta-analysis results	11 / 22	0.91 [0.82; 1.01], 8 RCTs, I2=38% inconclusive result	1.04 [0.67; 1.62], 1 RCT, I2=0% inconclusive result	0.92 [0.84; 1.00], 2 RCTs, I2=0% inconclusive result
study description meta-analysis results	10	0.83 [0.63; 1.09], 6 RCTs, I2=26% inconclusive result	1.30 [1.15; 1.46], 4 RCTs, I2=0% conclusive moderate degree of certainty	0.97 [0.85; 1.10], 1 RCT, I2=0% inconclusive result
study description meta-analysis results	38 / 51	0.98 [0.92; 1.04], 37 RCTs, I2=0% inconclusive result	1.09 [0.87; 1.38], 8 RCTs, I2=39% inconclusive result	0.98 [0.94; 1.03], 5 RCTs, I2=0% inconclusive result
study description meta-analysis results	4 / 7	0.68 [0.51; 0.91], 4 RCTs, I2=65% conclusive high degree of certainty	1.24 [1.03; 1.48], 3 RCTs, I2=46% conclusive high degree of certainty	0.82 [0.65; 1.05], 2 RCTs, I2=58% inconclusive result
study description meta-analysis results	1 / 2		-	-
study description meta-analysis results	1 / 2	0.49 [0.15; 1.62], 1 RCT, I2=0% inconclusive result	-	0.63 [0.41; 0.97], 1 RCT, I2=0% conclusive unassessable degree of certainty
study description meta-analysis results	2	0.75 [0.60; 0.94], 2 RCTs, I2=33% conclusive moderate degree of certainty	-	0.79 [0.65; 0.95], 2 RCTs, I2=34% moderate degree of certainty
study description meta-analysis results	12 / 16	0.86 [0.53; 1.41], 9 RCTs, I2=20% inconclusive result	1.39 [0.78; 2.47], 4 RCTs, I2=68% inconclusive result	0.83 [0.35; 1.93], 2 RCTs, I2=46% inconclusive result
study description meta-analysis results	22 / 38	0.85 [0.77; 0.92], 20 RCTs, I2=0% conclusive safety concern inconclusive result	1.26 [1.04; 1.52], 5 RCTs, I2=36% conclusive moderate degree of certainty	0.83 [0.72; 0.96], 7 RCTs, I2=17% conclusive moderate degree of certainty
study description meta-analysis results	4 / 7	0.89 [0.52; 1.53], 3 RCTs, I2=0% inconclusive result	1.03 [0.75; 1.41], 1 RCT, I2=0% inconclusive result	1.12 [0.56; 2.22], 1 RCT, I2=0% inconclusive result
study description meta-analysis results	4 / 5	1.06 [0.83; 1.37], 3 RCTs, I2=39% inconclusive result	0.83 [0.67; 1.03], 1 RCT, I2=0% inconclusive result	0.82 [0.63; 1.07], 1 RCT, I2=0% inconclusive result
study description meta-analysis results	1	1.09 [0.78; 1.53], 1 RCT, I2=0% inconclusive result	-	-

Statistically conclusive: statistically significant with a strict control of overall risk of type 1 error (statistically demonstrated), does not take into account the risk of bias; suggested: nominally statistically significant but without a strict control of overall risk of type 1 error; inconclusive: not nominally statistically significant

149
treatments

718
studies with results

1743
studies screend

1629
references

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N), Université de Lyon (UdL/Idex), and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

- About - Our approach - Credits - RSS Made with in Lyon - Contact us - Privacy policy -