Study explorer (study characteristics and results) method abbreviations pdf   xlsx

display ongoing studies
Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results deaths Eclinical improvement Edeath or ventilation E

COVID 19 hospitalized meta-analysis

Ranjbar, 2021
  IRCT20200204046369N1		 RCTmethylprednisolonedexamethasoneCOVID 19 hospitalizedsome concern
44/42 suggested -54%
Metcovid, 2020
  NCT04343729		 RCTmethylprednisoloneplaceboCOVID 19 hospitalizedsome concern
209/207 inconclusive -7%
RECOVERY dexamethasone, 2020
  NCT04381936		 RCTdexamethasonestandard of careCOVID 19 hospitalizedsome concern
2104/4321 conclusif demonstrated-15% -7%
Tang X, 2020
  NCT04273321		 RCTmethylprednisoloneplaceboCOVID 19 hospitalizedsome concern
43/43 suggested -2% 4%

COVID-19 severe or critically meta-analysis

COVID STEROID 2, 2021
  NCT04509973		 RCTDexamethasone 12mgdexamethasone 6mgCOVID-19 severe or criticallylow
497/485 inconclusive -13%
Jamaati, 2021
  IRCT20151227025726N1		 RCTdexamethasonestandard of careCOVID-19 severe or criticallysome concern
25/25 suggested 17%
Munch (COVID-STEROID), 2021
  NCT04348305		 RCTHydrocortisoneplaceboCOVID-19 severe or criticallylow
16/14 no results
CAPE-COVID, 2020
  NCT02517489		 RCTHydrocortisoneplaceboCOVID-19 severe or criticallylow
76/73 inconclusive -50% -26%
CODEX (Tomazini), 2020
  NCT04327401		 RCTdexamethasonestandard of careCOVID-19 severe or criticallysome concern
151/148 inconclusive -3%
DEXA-COVID19, 2020
  NCT04325061		 RCTdexamethasonestandard of careCOVID-19 severe or criticallylow
7/12 inconclusive 90%
Steroids-SARI, 2020
  NCT04244591		 RCTmethylprednisolonestandard of careCOVID-19 severe or criticallysome concern
24/23 inconclusive -8%
10 studies excluded by filtering options (6 RCT / 4 OBS)

PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

 

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