Meta-analysis results for all treatments

Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method

Treament Trials      
clinical deteriorationclinical improvementdeathsPCR-negative conversion
Immunosuppressants drugs16 1.11 [0.59; 2.09], 1 RCT, I2=0%
inconclusive result
1.41 [1.14; 1.74], 6 RCTs, I2=36% demonstrated
low degree of certainty
0.95 [0.67; 1.36], 7 RCTs, I2=47%
safety concern
inconclusive result
-
Immunostimulants drugs13- 1.04 [0.61; 1.78], 2 RCTs, I2=51%
inconclusive result
0.95 [0.58; 1.56], 4 RCTs, I2=0%
inconclusive result
-
corticosteroids10 0.96 [0.47; 1.94], 2 RCTs, I2=84%
inconclusive result
1.16 [0.84; 1.60], 2 RCTs, I2=0%
inconclusive result
0.84 [0.60; 1.17], 5 RCTs, I2=70% demonstrated
inconclusive result
-
A EFFACER anticorps0----
acalabrutinib0----
anti-inflammatory therapies0----
Apilimod0----
imatinib0----
leflunomide0----
pirfenidone0----
Polyinosinic-Polycytidylic Acid0----
sargramostim0----
thymosin0----