Meta-analysis results for all treatments

Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method

Treament Trials      
clinical improvementclinical worseningdeathsPCR-negative conversion
Immunosuppressants drugs13 1.21 [0.96; 1.52], 4 RCTs, I2=9%
inconclusive result
1.11 [0.59; 2.09], 1 RCT, I2=0%
inconclusive result
1.09 [0.76; 1.56], 4 RCTs, I2=0%
inconclusive result
-
corticosteroids10 1.16 [0.84; 1.60], 2 RCTs, I2=0%
inconclusive result
0.66 [0.43; 1.02], 1 RCT, I2=0%
inconclusive result
0.77 [0.60; 0.99], 6 RCTs, I2=65% demonstrated
low degree of certainty
-
Immunostimulants drugs5 1.40 [0.79; 2.49], 1 RCT, I2=0%
inconclusive result
- 0.59 [0.22; 1.59], 1 RCT, I2=0%
inconclusive result
-
acalabrutinib0----
anti-inflammatory therapies0----
anticorps0----
Apilimod0----
imatinib0----
leflunomide0----
pirfenidone0----
Polyinosinic-Polycytidylic Acid0----
sargramostim0----
thymosin0----