Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method
Treament | Trials | |||||
---|---|---|---|---|---|---|
clinical deterioration | clinical improvement | deaths | viral clearance | |||
Immunosuppressants drugs | 1.11 [0.59; 2.09], 1 RCT, I2=0% inconclusive result | 1.06 [0.80; 1.41], 1 RCT, I2=0% inconclusive result | 0.87 [0.78; 0.99], 3 RCTs, I2=0% demonstrated moderate degree of certainty | - | ||
Immunostimulants drugs | - | - | 2.00 [0.16; 24.66], 1 RCT, I2=0% inconclusive result | - | ||
leflunomide | - | - | - | - | ||
anti-inflammatory therapies | 0 | - | - | - | - | |
Apilimod | 0 | - | - | - | - | |
corticosteroids | 0 | - | - | - | - | |
inhaled corticosteroids | 0 | - | - | - | - | |
Kinase inhibitors | 0 | - | - | - | - | |
meplazumab | 0 | - | - | - | - | |
pirfenidone | 0 | - | - | - | - | |
Polyinosinic-Polycytidylic Acid | 0 | - | - | - | - | |
sargramostim | 0 | - | - | - | - | |
statins | 0 | - | - | - | - | |
thymosin | 0 | - | - | - | - |