meta|Evidence - COVID-19
Member of the meta|Evidence galaxy
Treament | Trials | |||||
---|---|---|---|---|---|---|
Statistically conclusive or suggested result | Inconclusive results | Uncertain results | Safety results | |||
|
0 | - | - | - | - | |
|
7 / 16 | none | inconclusive results for: death D28; deaths; deaths (time to event analysis only); clinical deterioration; clinical improvement; clinical improvement (14-day); clinical improvement (time to event analysis only); death or ventilation; hospital discharge; mechanical ventilation; serious adverse events; superinfection | - | ||
|
1 | none | inconclusive results for: deaths; clinical deterioration; clinical improvement; clinical improvement (14-day); clinical improvement (28-day); clinical improvement (7-day); clinical improvement (time to event analysis only); AE leading to drug discontinuation; serious adverse events; deep vein thrombosis; elevated liver enzymes; hyperbilirubinemia; pulmonary embolism; renal impairment | - | - | |
|
11 / 18 | none | inconclusive results for: 14-days deaths; death D28; deaths; deaths (time to event analysis only); clinical deterioration; clinical improvement; clinical improvement (14-day); clinical improvement (28-day); clinical improvement (7-day); clinical improvement (time to event analysis only); mechanical ventilation; mechanical ventilation (time to event analysis only); viral clearance ; viral clearance by day 14; ICU admission; off oxygenation; serious adverse events; adverse events | - | - | |
|
1 / 2 | none | inconclusive results for: death or transfer to ICU; clinical improvement (14-day); clinical improvement (28-day); ICU admission; recovery; acute kidney injury ; arrhythmia; elevated liver enzymes; Myocardial infarction ; venous thromboembolism | suggested 46 % decrease in death D28 but the degree if certainty is unassessable suggested 46 % decrease in deaths but the degree if certainty is unassessable suggested 2.9-fold increase in clinical improvement but the degree if certainty is unassessable | - | |
|
1 / 2 | none | inconclusive results for: deaths | - | - | |
|
0 | - | - | - | - | |
|
0 | - | - | - | - | |
|
4 / 5 | statistically conclusive 66 % increase in clinical improvement (time to event analysis only) | inconclusive results for: death D28; deaths; deaths (time to event analysis only); clinical improvement; clinical improvement (14-day); hospital discharge; mechanical ventilation; ICU admission; off oxygenation; superinfection | - | - | |
|
8 / 18 | statistically conclusive 44 % increase in clinical improvement | inconclusive results for: deaths (time to event analysis only); clinical deterioration; clinical improvement (28-day); clinical improvement (time to event analysis only); death or ventilation; hospital discharge; mechanical ventilation; recovery; serious adverse events; superinfection; adverse events | suggested 52 % decrease in ICU admission but the degree if certainty is unassessable | ||
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3 / 6 | none | inconclusive results for: deaths; deaths (time to event analysis only); clinical improvement; clinical improvement (14-day); clinical improvement (time to event analysis only); serious adverse events; adverse events | - | - | |
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2 | none | inconclusive results for: deaths; clinical improvement; Major thrombotic events or death; Major bleeding | - | - | |
|
1 | none | inconclusive results for: deaths; Major bleeding; Thromboembolic events | - | - |
Statistically conclusive: statistically significant with a strict control of overall risk of type 1 error (statistically demonstrated), does not take into account the risk of bias; suggested: nominally statistically significant but without a strict control of overall risk of type 1 error; inconclusive: not nominally statistically significant
149
treatments |
718
studies with results |
1743
studies screend |
1629
references |
This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N), Université de Lyon (UdL/Idex), and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.
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