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meta|Evidence - COVID-19

Live meta-analysis and evidence synthesis of potential therapies for COVID19

  Summary of results of all meta-analysis  
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Our approach

Latest studies

hydroxychloroquine vs. placebo - COVID-19 prophylaxis low risk of bias

  • inconclusive results for: PCR positive or probable Covid-19; PCR confirmed Covid-19

meta-analysis

hydroxychloroquine vs. placebo - COVID-19 prophylaxis low risk of bias

  • inconclusive results for: PCR positive or probable Covid-19; PCR confirmed Covid-19

meta-analysis

PATCH PreP (Abella) , 2020   NCT04329923 yesterday

hydroxychloroquine vs. placebo - COVID-19 prophylaxis some concern in risk of bias

  • inconclusive results for: PCR confirmed infection rate

meta-analysis

Edalatifard , 2020   IRCT20200404046947N1 9 days ago

corticosteroids vs. control - COVID-19 severe or critically high risk of bias

  • suggested 71 % decrease in death but with a low degree of certainty due to high risk of bias

meta-analysis

PLACID , 2020   CTRI/2020/04/024775 3 weeks ago

convalescent plasma treatment vs. control - COVID 19 hospitalized high risk of bias

  • inconclusive results for: 28-day death

meta-analysis

ConPlas-19 , 2020   NCT04345523 4 weeks ago

convalescent plasma treatment vs. standard of care - COVID 19 hospitalized some concern in risk of bias

  • inconclusive results for: time to improvement; overall survival

meta-analysis

COALITION II (Furtado) , 2020   NCT04321278 4 weeks ago

azithromycin vs. control - COVID-19 severe or critically some concern in risk of bias

  • inconclusive results for: Score on six-point ordinal scale at day 15; Death at 29 days

meta-analysis

COVACTA (Rosas) , 2020   NCT04320615 4 weeks ago

tocilizumab vs. placebo - COVID-19 severe or critically some concern in risk of bias

  • inconclusive results for: Clinical status at day 28; Mortality at day 28; Serious infections

meta-analysis

CAPE-COVID , 2020   NCT02517489 4 weeks ago

corticosteroids vs. placebo - COVID-19 severe or critically low risk of bias

  • inconclusive results for: death; nosocomial infections

meta-analysis

REMAP-CAP, fixed 7-day course , 2020   NCT02735707 4 weeks ago

corticosteroids vs. control - COVID-19 severe or critically some concern in risk of bias

  • inconclusive results for: WHO scale at day 14d; death

meta-analysis

Follow-us

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N) and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

   

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