published meta-analysis   sensitivity analysis   studies

potential COVID-19 treatments in COVID 19 outpatients - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsPRINCIPLE, 2021 1.65 [0.03; 83.12] 1.65[0.03; 83.12]PRINCIPLE, 202110%1,323NAnot evaluable hospitalization or deathdetailed resultsHinks (ATOMIC2), 2021 0.91 [0.43; 1.92] 0.91[0.43; 1.92]Hinks (ATOMIC2), 202110%292NAnot evaluable A EFFACER PCR-negative (end of follow-up)detailed resultsHinks (ATOMIC2), 2021 0.91 [0.57; 1.46] 0.91[0.57; 1.46]Hinks (ATOMIC2), 202110%295NAnot evaluable clinical improvementdetailed resultsPRINCIPLE, 2021 1.08 [0.95; 1.23] 1.08[0.95; 1.23]PRINCIPLE, 202110%1,323NAnot evaluable clinical improvement (14-day)detailed resultsACTION, 2021 1.01 [0.75; 1.37] 1.01[0.75; 1.37]ACTION, 202110%263NAnot evaluable clinical improvement (time to event analysis only)detailed resultsPRINCIPLE, 2021 1.08 [0.95; 1.23] 1.08[0.95; 1.23]PRINCIPLE, 202110%1,323NAnot evaluable hospitalizationdetailed resultsHinks (ATOMIC2), 2021 0.95 [0.46; 1.96] PRINCIPLE, 2021 0.94 [0.50; 1.75] 0.94[0.59; 1.51]Hinks (ATOMIC2), 2021, PRINCIPLE, 202120%1,618moderatenot evaluable mechanical ventilationdetailed resultsPRINCIPLE, 2021 0.50 [0.10; 2.60] 0.50[0.10; 2.60]PRINCIPLE, 202110%1,121NAnot evaluable ICU admissiondetailed resultsPRINCIPLE, 2021 0.76 [0.18; 3.18] 0.76[0.18; 3.18]PRINCIPLE, 202110%1,120NAnot evaluable0.25.01.0relative treatment effectwww.metaEvidence.org2024-05-01 03:50 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 97 - treatments: 290,547,608,830,831,829,901,680,595,828,681,1209,833,629,689,543,617,625,859,511,960,546,564,944,682,1266,943,894,560,1102,598,563,668,753,752,836,639,541,534,581,615,679,522,582,666,1149,1150,737,544,733,597,524,611,538,957,958,521,566,517,881,904,882,897,896,899,1235,898,687,740,883,947,536,591,729,887,742,878,975,570,771,888,1141,690,880,1255,567,596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526,616,926,1246,726,580,568,527,588,539,585,691,1210,525,843,827,1047,1048,819,545,1253,519,619,537,514,688,529,508,656,657,832,530,512,515,754,1142,1419,513,884,632,559,889,956,684,886,631,574,509,542,1145,555,554,941,961,1250,633,676,518,532,510,528,520,955,815,893,623,622,630,593,569,516,814,649,650,589,651,968,1245,610,751,747,695,548,970,594,565,879,1257,571,626,697,572,1234,586,573,540,592,930,949,838,698,934,735,929,948,946,945,587,655,1146,531,933,613,919,725,678,921,621,959,748,1348,1256,924,1243,925,658,699,612,552,590,891,605,892,722,618,609,551,834,763,922,935,620,1317,1265,824,766,857,1291,1088,1331,1330,1329,1344,1328,1327,979,822,762,805,950,757,761,806,758,826,755,821,1288,1287,1286,760,1284,802,765,1285,759,823,804,1264,764,858,835,1262,1290,1316,1341,1342,1343,825,803,1244,523,885,734,1439 - roots T: 290