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meta|Evidence - COVID-19

Living meta-analysis and evidence synthesis of therapies for COVID19  

Member of the meta|Evidence galaxy

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Treament Trials
Statistically conclusive or suggested result Inconclusive results Uncertain results Safety results
0 / 1 noneinconclusive results for: hospitalization or death--
2 noneinconclusive results for: death D28; deaths; hospitalization or death; clinical improvement (14-day); clinical improvement (28-day); clinical improvement (7-day); hospitalization; recovery; adverse events--
1

statistically conclusive 87 % decrease in hospitalization or death

suggested 72 % decrease in hospitalization

suggested 75 % decrease in serious adverse events

inconclusive results for: death D28; deaths; AE leading to drug discontinuation; adverse events--
1 noneinconclusive results for: death D28; deaths; hospitalization or death; hospitalization; mechanical ventilation--
0- - - -
0- - - -
0- - - -
2

statistically conclusive 71 % decrease in hospitalization or death

statistically conclusive 44 % decrease in symptomatic Covid-19

suggested 45 % decrease in adverse events

inconclusive results for: deaths; hospitalization; serious adverse events--
1 / 3

statistically conclusive 4.1-fold increase in viral clearance by day 7

inconclusive results for: Emergency room visit or hospitalization; death D28; deaths; hospitalization; viral clearance (time to event analysis only)--
0- - - -
0- - - -
0- - - -
0- - - -

Statistically conclusive: statistically significant with a strict control of overall risk of type 1 error (statistically demonstrated), does not take into account the risk of bias; suggested: nominally statistically significant but without a strict control of overall risk of type 1 error; inconclusive: not nominally statistically significant

148
treatments
  701
studies with results
  1719
studies screend
  1590
references

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N), Université de Lyon (UdL/Idex), and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

     

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