| display ongoing studies | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Study | Ref. | Design | studied treatment | control treatment | patients | study risk of bias | sample sizes | Results | symptomatic Covid-19 E | new illness compatible with Covid-19 E | conversion to SARS-CoV- 2–positive status via NP swab E | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
COVID 19 outpatients meta-analysis | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| CoV-Early (Gharbharan) NCT04589949 | RCT | convalescent plasma treatment | placebo | COVID 19 outpatients | low | 207/209 | inconclusive | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| CONV-ERT NCT04621123 | RCT | convalescent plasma treatment | placebo | COVID 19 outpatients | low | 188/160 | inconclusive | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| C3PO NCT04355767 | RCT | convalescent plasma treatment | placebo | COVID 19 outpatients | some concern | 257/254 | inconclusive | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).
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