published meta-analysis   sensitivity analysis   studies

anti-inflammatoty and immuno-therapy in COVID 19 outpatients - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsPRINCIPLE (COLCHICINE), 2021 0.42 [0.01; 12.75] 0.42[0.01; 12.75]PRINCIPLE (COLCHICINE), 202110%289NAnot evaluable deathsdetailed resultsPRINCIPLE (COLCHICINE), 2021 0.42 [0.01; 12.75] 0.42[0.01; 12.75]PRINCIPLE (COLCHICINE), 202110%289NAnot evaluable hospitalization or deathdetailed resultsPRINCIPLE, 2021 0.81 [0.58; 1.13] PRINCIPLE (COLCHICINE), 2021 1.29 [0.36; 4.67] 0.83[0.60; 1.16]PRINCIPLE, 2021, PRINCIPLE (COLCHICINE), 202120%1,949moderatenot evaluable clinical improvementdetailed resultsPRINCIPLE, 2021 1.21 [1.08; 1.36] 1.21[1.08; 1.36]PRINCIPLE, 202110%1,779NAnot evaluable hospitalizationdetailed resultsPRINCIPLE (COLCHICINE), 2021 1.73 [0.43; 7.07] 1.73[0.43; 7.07]PRINCIPLE (COLCHICINE), 202110%289NAnot evaluable mechanical ventilationdetailed resultsPRINCIPLE, 2021 1.02 [0.45; 2.33] 1.02[0.45; 2.33]PRINCIPLE, 202110%1,503NAnot evaluable ICU admissiondetailed resultsPRINCIPLE, 2021 0.54 [0.24; 1.21] 0.54[0.24; 1.21]PRINCIPLE, 202110%1,491NAnot evaluable recoverydetailed resultsPRINCIPLE, 2021 1.21 [1.08; 1.36] PRINCIPLE (COLCHICINE), 2021 0.92 [0.72; 1.17] 1.08[0.83; 1.40]PRINCIPLE, 2021, PRINCIPLE (COLCHICINE), 2021275%4,072moderatenot evaluable0.25.01.0relative treatment effectwww.metaEvidence.org2024-05-05 23:18 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 97 - treatments: 546,564,944,682,1266,943,894,560,1102,598,563,668,753,752,836,639,541,534,581,615,679,522,582,666,1149,1150,737,544,733,597,524,611,538,957,958,521,566,517,881,904,882,897,896,899,1235,898,687,740,883,947,536,591,729,887,742,878,975,570,771,888,1141,690,880,1255,567,596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526,616,926,1246,726,580,568,527,588,539,585,691,1210,525 - roots T: 290