published meta-analysis   sensitivity analysis   studies

antiviral and associated therapy in COVID-19 mild to moderate - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsKirti, 2021 0.12 [0.01; 2.36] 0.12[0.01; 2.36]Kirti, 202110%112NAnot evaluable clinical improvement (7-day)detailed resultsKirti, 2021 0.90 [0.77; 1.06] 0.90[0.77; 1.06]Kirti, 202110%112NAnot evaluable clinical improvement (time to event analysis only)detailed resultsShinkai, 2021 1.40 [0.91; 2.15] 1.40[0.91; 2.15]Shinkai, 202110%156NAnot evaluable hospital dischargedetailed resultsKirti, 2021 1.20 [0.73; 1.98] 1.20[0.73; 1.98]Kirti, 202110%112NAnot evaluable mechanical ventilationdetailed resultsKirti, 2021 0.20 [0.00; 8.69] 0.20[0.00; 8.69]Kirti, 202110%112NAnot evaluable viral clearance detailed resultsChaccour, 2020 0.92 [0.77; 1.09] 0.92[0.77; 1.09]Chaccour, 202010%24NAnot evaluable viral clearance by day 7detailed resultsChaccour, 2020 0.92 [0.77; 1.09] Kirti, 2021 0.80 [0.43; 1.50] 0.91[0.77; 1.08]Chaccour, 2020, Kirti, 202120%136lownot evaluable ICU admissiondetailed resultsKirti, 2021 0.90 [0.30; 2.70] 0.90[0.30; 2.70]Kirti, 202110%112NAnot evaluable serious adverse eventsdetailed resultsShinkai, 2021 2.80 [0.14; 56.95] 2.80[0.14; 56.95]Shinkai, 202110%156NAnot evaluable adverse eventsdetailed resultsChaccour, 2020 1.00 [0.20; 5.07] Shinkai, 2021 19.54 [7.77; 49.11] 4.78[0.26; 87.65]Chaccour, 2020, Shinkai, 2021290%180moderatenot evaluable0.010.01.0relative treatment effectwww.metaEvidence.org2024-05-01 17:10 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 90 - treatments: 545,1253,519,619,537,514,688,529,508,656,657,832,530,512,515,754,1142,1419,513,884,632,559,889,956,684,886,631,574,509,542,1145,555,554,941,961,1250,633,676,518,532,510,528,520,955,815,893,623,622,630,593,569,516,814 - roots T: 290