published meta-analysis   sensitivity analysis   studies

vitamin C in COVID-19 severe or critically - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsZhang, 2020 0.50 [0.17; 1.50] 0.50[0.17; 1.50]Zhang, 202010%56NAnot evaluable deathsdetailed resultsCao, 2020 (REV) 6.50 [0.30; 138.87] Zhang, 2020 0.50 [0.17; 1.50] 1.19[0.11; 12.85]Cao, 2020 (REV), Zhang, 2020258%97moderatenot evaluable deaths (time to event analysis only)detailed resultsZhang, 2020 0.50 [0.17; 1.50] 0.50[0.17; 1.50]Zhang, 202010%56NAnot evaluable clinical deteriorationdetailed resultsCao, 2020 (REV) 9.18 [0.45; 186.37] Zhang, 2020 0.87 [0.23; 3.27] 1.89[0.22; 16.48]Cao, 2020 (REV), Zhang, 2020249%97moderatenot evaluable clinical improvementdetailed resultsCao, 2020 (REV) 0.60 [0.30; 1.20] 0.60[0.30; 1.20]Cao, 2020 (REV)10%42NAnot evaluable clinical improvement (14-day)detailed resultsCao, 2020 (REV) 0.50 [0.14; 1.73] 0.50[0.14; 1.73]Cao, 2020 (REV)10%41NAnot evaluable clinical improvement (21-day)detailed resultsCao, 2020 (REV) 0.67 [0.10; 4.48] 0.67[0.10; 4.48]Cao, 2020 (REV)10%41NAnot evaluable clinical improvement (7-day)detailed resultsCao, 2020 (REV) 0.42 [0.07; 2.61] 0.42[0.07; 2.61]Cao, 2020 (REV)10%41NAnot evaluable clinical improvement (time to event analysis only)detailed resultsCao, 2020 (REV) 0.60 [0.30; 1.20] 0.60[0.30; 1.20]Cao, 2020 (REV)10%42NAnot evaluable radiologic improvement (14-day)detailed resultsCao, 2020 (REV) 0.18 [0.03; 0.99] 0.18[0.03; 0.99]Cao, 2020 (REV)10%41NAnot evaluable serious adverse eventsdetailed resultsCao, 2020 (REV) 9.18 [0.45; 186.37] 9.18[0.45; 186.37]Cao, 2020 (REV)10%41NAnot evaluable adverse eventsdetailed resultsCao, 2020 (REV) 0.63 [0.15; 2.66] 0.63[0.15; 2.66]Cao, 2020 (REV)10%41NAnot evaluable0.020.01.0relative treatment effectwww.metaEvidence.org2024-04-28 09:34 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 91 - treatments: 523,885 - roots T: 290