published meta-analysis   sensitivity analysis   studies

chloroquine and derivatives in COVID 19 hospitalized - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsGalan, 2021 (REV) 1.06 [0.58; 1.95] HAHPS, 2020 7.00 [0.80; 60.90] 2.03[0.35; 11.68]Galan, 2021 (REV), HAHPS, 2020263%253moderatenot evaluable deaths (time to event analysis only)detailed resultsGalan, 2021 0.94 [0.51; 1.73] 0.94[0.51; 1.73]Galan, 202110%168NAnot evaluable clinical deteriorationdetailed resultsHAHPS, 2020 1.07 [0.63; 1.82] 1.07[0.63; 1.82]HAHPS, 202010%NAnot evaluable clinical improvementdetailed resultsHuang, 2020 1.37 [0.73; 2.56] 1.37[0.73; 2.56]Huang, 202010%22NAnot evaluable clinical improvement (14-day)detailed resultsHuang, 2020 1.37 [0.73; 2.56] 1.37[0.73; 2.56]Huang, 202010%22NAnot evaluable hospital dischargedetailed resultsHAHPS, 2020 0.91 [0.54; 1.54] Huang, 2020 2.00 [1.15; 3.47] 1.34[0.62; 2.90]HAHPS, 2020, Huang, 2020276%107moderatenot evaluable mechanical ventilationdetailed resultsGalan, 2021 0.14 [0.03; 0.71] 0.14[0.03; 0.71]Galan, 202110%168NAnot evaluable radiologic improvement (14-day)detailed resultsHuang, 2020 1.33 [0.94; 1.88] 1.33[0.94; 1.88]Huang, 202010%22NAnot evaluable radiologic improvement (7-day)detailed resultsHuang, 2020 2.40 [0.26; 22.51] 2.40[0.26; 22.51]Huang, 202010%22NAnot evaluable viral clearance detailed resultsHuang, 2020 1.20 [0.78; 1.85] 1.20[0.78; 1.85]Huang, 202010%22NAnot evaluable viral clearance by day 14detailed resultsHuang, 2020 1.09 [0.95; 1.26] 1.09[0.95; 1.26]Huang, 202010%22NAnot evaluable viral clearance by day 7detailed resultsHuang, 2020 1.20 [0.60; 2.40] 1.20[0.60; 2.40]Huang, 202010%22NAnot evaluable ICU admissiondetailed resultsGalan, 2021 1.42 [0.68; 2.99] 1.42[0.68; 2.99]Galan, 202110%168NAnot evaluable adverse eventsdetailed resultsHuang, 2020 1.80 [0.14; 23.37] 1.80[0.14; 23.37]Huang, 202010%22NAnot evaluable0.05.01.0relative treatment effectwww.metaEvidence.org2024-04-26 09:53 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 95,94,90,91 - treatments: 508,656,657,832 - roots T: 290