All patients
age >= 60 yr age >= 65 yr corticosteroids: no corticosteroids: yes invasive ventilation non invasive oxygen subjects at risk
antiviral and associated therapy in COVID-19 (hospitalized or not) - Summary of results Outcome TE 95% CI n k I2 ROB Pub. bias deathsdetailed results Abd-Elsalam, 2020 0.99 [0.28; 3.53]
0.99 [0.28 ; 3.53 ] Abd-Elsalam, 2020 1 0% 191 NA not evaluable clinical improvementdetailed results Abd-Elsalam, 2020 1.08 [0.54; 2.15]
Chang Chen et al., 2020 1.48 [0.88; 2.48]
1.32 [0.87 ; 2.00 ] Abd-Elsalam, 2020, Chang Chen et al., 2020 2 0% 427 moderate not evaluable clinical improvement (28-day)detailed results Abd-Elsalam, 2020 1.08 [0.54; 2.15]
1.08 [0.54 ; 2.15 ] Abd-Elsalam, 2020 1 0% 191 NA not evaluable clinical improvement (7-day)detailed results Chang Chen et al., 2020 1.48 [0.88; 2.48]
1.48 [0.88 ; 2.48 ] Chang Chen et al., 2020 1 0% 236 NA not evaluable mechanical ventilationdetailed results Abd-Elsalam, 2020 0.64 [0.18; 2.36]
0.64 [0.18 ; 2.36 ] Abd-Elsalam, 2020 1 0% 191 NA not evaluable radiologic improvement (14-day)detailed results Hong Zhao, 2021 3.16 [0.62; 16.10]
3.16 [0.62 ; 16.10 ] Hong Zhao, 2021 1 0% 12 NA not evaluable viral clearance by day 7detailed results NCT04429711 (Biber), 2020 2.62 [1.06; 6.46]
2.62 [1.06 ; 6.46 ] NCT04429711 (Biber), 2020 1 0% 100 NA not evaluable serious adverse eventsdetailed results Hong Zhao, 2021 1.44 [0.02; 87.17]
1.44 [0.02 ; 87.17 ] Hong Zhao, 2021 1 0% 12 NA not evaluable 0.2 5.0 1.0 relative treatment effect www.metaEvidence.org 2024-05-04 22:06 +02:00
TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers);
k: number of studies; n: total number of patients;
ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1;
studied treatment is better when TE < 1;
pathologies: 87
- treatments: 545,1253,519,619,537,514,688,529,508,656,657,832,530,512,515,754,1142,1419,513,884,632,559,889,956,684,886,631,574,509,542,1145,555,554,941,961,1250,633,676,518,532,510,528,520,955,815,893,623,622,630,593,569,516,814
- roots T: 290