corticosteroids - for COVID-19 method

Outcome Relative effect 95%CI LoD Trt. better when I2 k (RCT/OBS) Bayesian probability Overall ROB Publication bias Degree of certainty Endpoint importance Published MA
clinical worsening 0.74 [0.30, 1.82]< 177%3 studies (1 / 2)74.5 %criticalnot evaluable very lowcrucial-
deaths 0.90 [0.53, 1.52]< 185%10 studies (1 / 9)65.6 %criticallow very lowcrucial-
deaths (time to event analysis only) 0.94 [0.10, 8.72]< 195%2 studies (- / 2)52.3 %criticalnot evaluable very lowcrucial-

LoD: level of demonstration ( demonstrated, suggested, inconclusive, safety concerns);
Bayesian probability: Bayesian posterior probability of treatment effect (computed with a noninformative prior); ROB: risk of bias; k: number of studies; published MA: number of published meta-analysis on the same topic; degree of certainty adapted from GRADE. Trt. better when: indicates when the relative treatment effect shows that the studied treatment is better than control.



This meta-analysis covered 2 pathologies: 87,95,94,90,91,97 95, 91