table network network 2
demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only
COVID 19 all comersCOVID-19 mild to moderateCOVID-19 severe or critically
COVID 19 hospitalizedCOVID 19 all comersCOVID-19 mild to moderateCOVID-19 severe or critically
Immunostimulants drugs
convalescent plasma treatment ConPlas-19 CPC-SARS COPLA-II trial Bennett-Guerrero COP-COVID-19 NCT04403477 ... CONTAIN COVID-19 NCT04442191 LACCPT ASCOT PERUCONPLASMA Co-CLARITY Baldeon PC/COVID-19 DAWN-Plasma RECOVERY ... NCT04528368 Menichetti NCT04397757 NCT04385199 Salman Holm K ConCOVID ... PLACO-COVID Kirenga CCAP-2 CONCOR-1 CONFIDENT LIFESAVER Libster PLACID CP-COVID-19 RECOVER ILBS-COVID-02 ... PICP19 ... Pouladzadeh Rasheed AlQahtani O’Donnell PlasmAr Sekine ... Li CAPSID REMAP-CAP ... Ray
Early convalescent plasma. Balcells
immunoglobulin therapy Sakoulas Parikh Raman Tabarsi Gharebaghi
interferon
IFN beta-1a SOLIDARITY ... Kalil ... Davoudi-Monfared Darazam ...
high-dose IFN beta-1a Darazam
IFN beta-1b Darazam ... Rahmani
IFN gamma Esquivel-Moynelo
inhaled interferon
IFN alpha
pegylated interferon-α2b Pandit Shashi Bhushan
recombinant super-compound interferon rSIFN-co Li
SNG001 inhaled interferon beta SPRINTER Synairgen SG016
interferon / TFF2 Fu
peginterferon Jagannathan
PNB001 Lattmann
neutralizing antibody ITAC
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences) ACTIV-3 ...
bamlanivimab monotherapy ACTIV-3/TICO LY-CoV555
casirivimab/imdevimab (Ronapreve) RECOVERY ... Somersan-Karakaya ...
cilgavimab and tixagevimab (Evusheld) ACTIV-3/TICO ...
equine polyclonal antibodies INM005 Lopardo
sotrovimab (Xevudy; VIR-7831) ACTIV-3/ TICO ...

14 studies excluded by filtering options 1

4861 Cai -FAVIPIRAVIR, 2020 1310not a RCTrisk of bias not avaialble
5183 Qiong Zhou, 2020 0190selection pending
5406 Duan, 2020 1134not a RCThigh risk of bias
5446 Sean, 2020 1134not a RCThigh risk of bias
5534 Wang (early IFN), 2020 0134selection pending
5549 Hegerova, 2020 1134not a RCThigh risk of bias
5550 Abolghasemi, 2020 1134not a RCThigh risk of bias
5569 Dai W, 2020 2134excludednot a RCThigh risk of bias
5572 Hao, 2020 0200selection pending
5662 Salazar, 2020 1134not a RCThigh risk of bias
5761 Joyner, 2020 1313not a RCThigh risk of bias
6140 Wang, 2020 0130selection pending
6159 Gemici, 2020 0130selection pending
6940 Bihariesingh-Sanchit (SuriCovid), 2021 1310not a RCTrisk of bias not avaialble

 

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