Immunostimulants drugs living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only

	COVID 19 all comers	COVID-19 mild to moderate

	COVID 19 hospitalized	COVID 19 all comers	COVID-19 mild to moderate
Immunostimulants drugs
convalescent plasma treatment	ConCOVID ... ConPlas-19 RECOVERY ... Co-CLARITY Menichetti COP-COVID-19 NCT04442191 Bennett-Guerrero NCT04528368 CONTAIN COVID-19 DAWN-Plasma Holm K PC/COVID-19 NCT04385199 Salman CCAP-2 NCT04397757 Kirenga PLACO-COVID COPLA-II trial CONFIDENT CONCOR-1 NCT04403477 ... PERUCONPLASMA CPC-SARS ASCOT LACCPT Baldeon	LIFESAVER	Libster PLACID
Early convalescent plasma.	Balcells
immunoglobulin therapy	Parikh Sakoulas
interferon
IFN beta-1a	SOLIDARITY ...
high-dose IFN beta-1a	Darazam
IFN gamma	Esquivel-Moynelo
inhaled interferon
IFN alpha
pegylated interferon-α2b			Pandit Shashi Bhushan
recombinant super-compound interferon rSIFN-co	Li
SNG001 inhaled interferon beta	Synairgen SG016 SPRINTER
interferon / TFF2			Fu
peginterferon			Jagannathan
PNB001			Lattmann
neutralizing antibody	ITAC
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences)	ACTIV-3 ...
bamlanivimab monotherapy	ACTIV-3/TICO LY-CoV555
casirivimab/imdevimab (Ronapreve)	RECOVERY ...		Somersan-Karakaya ...
cilgavimab and tixagevimab (Evusheld)	ACTIV-3/TICO ...
sotrovimab (Xevudy; VIR-7831)	ACTIV-3/ TICO ...