Living meta-analysis and evidence synthesis of therapies for COVID-19

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Ming Zhong, 2020 ChiCTR2000029851

alpha lipoic acid (n=8) vs. standard of care (n=9)

randomized controlled trial   high risk of bias

Studied treatment

α-Lipoic acid for
α-Lipoic acid ((1200 mg/d, intravenous infusion) once daily plus standard care

Control treatment

conventional therapy and placebo
equal volume saline infusion (placebo) for 7 days

Patients

COVID-19 severe or critically

Method

open-blind

single center, JinYinTan Hospital, Wuhan, China

Remark