× We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click our cookies policy for information on how to change your cookie settings.


meta|Evidence - COVID-19

Live meta-analysis and evidence synthesis of therapies for COVID19

PlasmAr , 2020   NCT04344535 6 days ago

convalescent plasma treatment vs. control - COVID-19 severe or critically low risk of bias

  • inconclusive results for: death; clinical improvement

meta-analysis

BCN PEP-CoV-2-Study 1 (Mitja NEJM) , 2020   NCT04304053 7 days ago

hydroxychloroquine vs. standard of care - COVID-19 prophylaxis some concern in risk of bias

  • inconclusive results for: death; PCR-confirmed, symptomatic Covid-19 disease; serious AE; any AE

meta-analysis

ORCHID , 2020   NCT04332991 3 weeks ago

hydroxychloroquine vs. placebo - COVID 19 hospitalized low risk of bias

  • inconclusive results for: deaths (28 days); COVID Outcomes Scale score at 14 d,; serious AE

meta-analysis

BACC Bay Tocilizumab Trial , 2020   NCT04356937 2 months ago

tocilizumab vs. placebo - COVID-19 severe or critically low risk of bias

  • inconclusive results for: death; mechanical ventilation or death; clinical improvement on ordinal scale; clinical worsening on ordinal scale

meta-analysis

CORIMUNO-19 , 2020   NCT04331808 2 months ago

tocilizumab vs. standard of care - COVID-19 mild to moderate some concern in risk of bias

  • inconclusive results for: death (day 28); WHO-CPS score greater than 5 at day 14; Mechanical Ventilation, or Death (day 14)

meta-analysis

RCT-TCZ-COVID-19 , 2020   NCT04346355 2 months ago

tocilizumab vs. standard of care - COVID-19 mild to moderate some concern in risk of bias

  • inconclusive results for: death before 30 days; clinical worsening 14 days

meta-analysis

SOLIDARITY (WHO study) HCQ , 2020   NCT04315948 2 months ago

hydroxychloroquine vs. standard of care - COVID 19 hospitalized some concern in risk of bias

  • inconclusive results for: 28 days death (rate ratio); death or initiation of ventilation

meta-analysis

SOLIDARITY (remdesivir) , 2020   NCT04315948 2 months ago

remdesivir vs. control - COVID 19 hospitalized some concern in risk of bias

  • inconclusive results for: in-hospital mortality; death or initiation of ventilation; initiation of ventilation

meta-analysis

SOLIDARITY (lopi/rito) , 2020   NCT04315948 2 months ago

lopinavir/ritonavir vs. standard of care - COVID 19 hospitalized some concern in risk of bias

  • inconclusive results for: in-hospital death

meta-analysis

SOLIDARITY (interferon) , 2020   NCT04315948 2 months ago

interferon vs. control - COVID 19 hospitalized some concern in risk of bias

  • inconclusive results for: In-hospital deaths; death or initiation of ventilation

meta-analysis

Follow-us

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N) and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

   

- About - Our approach - Credits Made with in Lyon - Contact us - Privacy policy - Licence Creative Commons