Living meta-analysis and evidence synthesis of therapies for COVID-19

 

• COVID 19 hospitalized
• COVID 19 all comers
• COVID-19 mild to moderate
• COVID-19 severe or critically
• COVID 19 outpatients
• COVID-19 (hospitalized or not)
• COVID-19 prophylaxis (children)
• COVID-19 prophylaxis (excluding children)
• infections other than COVID-19
• Long COVID-19
• preventing respiratory virus transmission
• secondary prevention

 

• adjuvant therapies
• anticoagulant
• enoxaparin
• hydrogen-oxygen nebulizer
• pulmonary rehabilitation
• anti-inflammatoty and immuno-therapy
• anti-inflammatory therapies
• colchicine
• sodium aescinate
• stem cells
• tradipitant
• corticosteroids
• ciclesonide
• low-dose corticosteroids
• Immunostimulants drugs
• anti-PD-1 antibody
• convalescent plasma treatment
• immunoglobulin therapy
• inactivated mycobacterium vaccine
• interferon
• Interleukin-2
• levamisole
• neutralizing antibody
• bevacizumab
• cilgavimab and tixagevimab (Evusheld)
• rhG-CSF
• Immunosuppressants drugs
• anakinra
• anti-interleukin-6
• sarilumab
• sarilumab high dose (400mg)
• sarilumab low dose (200mg)
• siltuximab
• tocilizumab
• emapalumab
• janus kinase (JAK) inhibitor
• baricitinib
• ruxolitinib
• tetrandrine
• thalidomide
• inhaled corticosteroids
• budesonide
• leflunomide
• pirfenidone
• Polyinosinic-Polycytidylic Acid
• thymosin
• antiviral and associated therapy
• ASC09/ritonavir
• baloxavir marboxil
• carrimycin
• chloroquine and derivatives
• chloroquine
• hydroxychloroquine
• danoprevir / ritonavir
• darunavir cobicistat
• darunavir/cobicistat plus chloroquine
• favipiravir
• hydroxychloroquine plus macrolides
• ivermectin
• lopinavir/ritonavir
• lopinavir/ritonavir plus interferon ß-1a
• lopinavir/ritonavir, ribavirin and interferon beta-1b
• nirmatrelvir / ritonavir (Paxlovid)
• nitazoxanide
• oseltamivir plus chloroquin
• remdesivir
• ritonavir
• tranilast
• triazavirin
• umifenovir (arbidol)
• control
• prone positioning
• Drugs for acid related disorders
• bismuth
• miscellaneous
• acetylcysteine
• alpha lipoic acid
• aviptadil
• camostat mesilate
• continuous positive airway pressure (CPAP)
• diammonium glycyrrhizinate
• dipyridamol
• natural killer (NK) cells
• nitric oxide (gas Inhalation or releasing solution)
• PUL-042 inhalation solution
• Oral antidiabetic drugs
• DPP-4 inhibitor
• Renin-angiotensin-system-acting agents
• angiotensin converting enzyme inhibitors (ACEIs)
• angiotensin receptor blockers (ARBs)
• losartan
• RAS blocker withdrawal
• rhACE2
• Vitamins
• vitamin C
• All treatment (not recommended)

    Top evidence (RCT only, high risk of bias excluded) Best available evidence (possibly low or very low) All RCTs All studies (RCT+OBS) see more...