Living meta-analysis and evidence synthesis of therapies for COVID-19

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Crippa (CANDIDATE), 2021 NCT04467918

Cannabidiol (n=53) vs. placebo (n=52)

randomized controlled trial   some concerns about risk of bias

Studied treatment

Cannabidiol
300mg/day Cannabidiol plus standard of care during 14 days.

Control treatment

Placebo
Placebo plus standard of care during 14 days.

Patients

COVID-19 mild to moderate

Method

Double-blind.

2 sites in Sao Paulo, Brazil.

Primary endpoint was measured with the COVID-19 Scale or the natural course of the resolution of typical clinical symptoms, and assessed on days 14, 21, and 28 after enrollment.

Remark