× We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click our cookies policy for information on how to change your cookie settings.


meta|Evidence - COVID-19

Live meta-analysis and evidence synthesis of therapies for COVID19

tutorial video
En     Fr

Our approach
     
Treament Trials
Demonstrated or suggested benefit Inconclusive results Uncertain results Safety results
corticosteroids0- - - -
remdesevir 3

demonstrated 38 % increase in clinical improvement

suggested 57 % increase in clinical improvement (14-day)

suggested 81 % increase in clinical improvement (28-day)

suggested 30 % increase in clinical improvement (7-day)

inconclusive results for: deaths--
chloroquine and derivatives 6 noneinconclusive results for: deaths; clinical improvement; clinical improvement (28-day); clinical improvement (time to event analysis only); clinical worsening; PCR-negative conversion; PCR-negative conversion (time to event analysis only); radiologic improvement (7-day); adverse events--
convalescent plasma treatment 1 noneinconclusive results for: death or transfer to ICU; deaths; PCR-negative conversion (7-day)--
interferon 2 noneinconclusive results for: clinical worsening; hospital discharge; PCR-negative conversion (time to event analysis only); adverse events--
anti-interleukin-6 4

demonstrated 44 % decrease in death or ventilation

inconclusive results for: deaths; deaths (time to event analysis only); clinical improvement; clinical improvement (time to event analysis only); clinical worsening; hospital discharge--
lopinavir/ritonavir 1

suggested 3.9-fold increase in clinical improvement

suggested 3.9-fold increase in clinical improvement (time to event analysis only)

demonstrated 3.2-fold increase in PCR-negative conversion

demonstrated 4.4-fold increase in PCR-negative conversion (time to event analysis only)

inconclusive results for: deaths; clinical worsening; PCR-negative conversion (14-day); PCR-negative conversion (7-day); radiologic improvement (14-day); radiologic improvement (7-day); serious adverse events--
anakinra 1 none---
colchicine 1 none---
anticoagulant0- - - -
Vitamin D 1 noneinconclusive results for: PCR-negative conversion--

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N) and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

   

- About - Our approach - Credits Made with in Lyon - Contact us - Privacy policy - Licence Creative Commons