published meta-analysis   sensitivity analysis   studies

anti-inflammatoty and immuno-therapy in COVID-19 mild to moderate - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsCOL-COVID (Pascual-Figal), 2021 0.24 [0.01; 5.41] Pandit, 2021 0.95 [0.02; 50.33] Shashi Bhushan, 2021 4.39 [0.20; 98.33] 1.01[0.15; 6.93]COL-COVID (Pascual-Figal), 2021, Pandit, 2021, Shashi Bhushan, 202130%392moderatenot evaluable deathsdetailed resultsCOL-COVID (Pascual-Figal), 2021 0.24 [0.01; 5.41] Fu, 2020 1.00 [0.02; 51.66] Pandit, 2021 0.95 [0.02; 50.33] Shashi Bhushan, 2021 4.39 [0.20; 98.33] 1.01[0.18; 5.69]COL-COVID (Pascual-Figal), 2021, Fu, 2020, Pandit, 2021, Shashi Bhushan, 202140%472moderatenot evaluable clinical deteriorationdetailed resultsCOL-COVID (Pascual-Figal), 2021 0.38 [0.09; 1.58] 0.38[0.09; 1.58]COL-COVID (Pascual-Figal), 202110%103NAnot evaluable clinical improvementdetailed resultsShashi Bhushan, 2021 0.68 [0.21; 2.20] 0.68[0.21; 2.20]Shashi Bhushan, 202110%242NAnot evaluable clinical improvement (14-day)detailed resultsPandit, 2021 8.77 [0.94; 81.67] Shashi Bhushan, 2021 0.68 [0.21; 2.20] 2.03[0.17; 24.32]Pandit, 2021, Shashi Bhushan, 2021275%281moderatenot evaluable clinical improvement (7-day)detailed resultsShashi Bhushan, 2021 1.91 [1.03; 3.53] 1.91[1.03; 3.53]Shashi Bhushan, 202110%222NAnot evaluable mechanical ventilationdetailed resultsCOL-COVID (Pascual-Figal), 2021 0.24 [0.01; 5.41] 0.24[0.01; 5.41]COL-COVID (Pascual-Figal), 202110%103NAnot evaluable radiologic improvement (14-day)detailed resultsRashad (CLARI vs SoC), 2021 2.87 [1.56; 5.28] 2.87[1.56; 5.28]Rashad (CLARI vs SoC), 202110%198NAnot evaluable viral clearance detailed resultsPandit, 2021 2.33 [0.55; 9.83] Shashi Bhushan, 2021 2.77 [1.44; 5.32] 2.69[1.48; 4.87]Pandit, 2021, Shashi Bhushan, 202120%281moderatenot evaluable viral clearance by day 14detailed resultsPandit, 2021 10.23 [1.12; 93.35] Shashi Bhushan, 2021 0.00 [0.00; 0.01] 0.18[0.00; 435.69]Pandit, 2021, Shashi Bhushan, 2021298%1,359moderatenot evaluable viral clearance by day 7detailed resultsPandit, 2021 2.33 [0.55; 9.83] Shashi Bhushan, 2021 2.77 [1.44; 5.32] 2.69[1.48; 4.87]Pandit, 2021, Shashi Bhushan, 202120%281moderatenot evaluable ICU admissiondetailed resultsCOL-COVID (Pascual-Figal), 2021 0.47 [0.08; 2.69] 0.47[0.08; 2.69]COL-COVID (Pascual-Figal), 202110%103NAnot evaluable serious adverse eventsdetailed resultsCOL-COVID (Pascual-Figal), 2021 0.24 [0.01; 5.41] Pandit, 2021 0.95 [0.02; 50.33] 0.40[0.03; 4.70]COL-COVID (Pascual-Figal), 2021, Pandit, 202120%142moderatenot evaluable adverse eventsdetailed resultsCOL-COVID (Pascual-Figal), 2021 1.72 [0.73; 4.08] Pandit, 2021 1.68 [0.47; 5.97] 1.71[0.84; 3.49]COL-COVID (Pascual-Figal), 2021, Pandit, 202120%142moderatenot evaluable0.05.01.0relative treatment effectwww.metaEvidence.org2024-05-05 17:40 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 90 - treatments: 546,564,944,682,1266,943,894,560,1102,598,563,668,753,752,836,639,541,534,581,615,679,522,582,666,1149,1150,737,544,733,597,524,611,538,957,958,521,566,517,881,904,882,897,896,899,1235,898,687,740,883,947,536,591,729,887,742,878,975,570,771,888,1141,690,880,1255,567,596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526,616,926,1246,726,580,568,527,588,539,585,691,1210,525 - roots T: 290