published meta-analysis   sensitivity analysis   studies

convalescent plasma treatment in COVID 19 hospitalized - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsConPlas-19, 2020 0.13 [0.01; 2.54] Gharbharan et al., 2020 0.95 [0.20; 4.59] Li, 2015 0.59 [0.22; 1.59] Libster, 2020 0.50 [0.09; 2.71] PlasmAr, 2020 0.93 [0.47; 1.85] 0.74[0.45; 1.23]ConPlas-19, 2020, Gharbharan et al., 2020, Li, 2015, Libster, 2020, PlasmAr, 202050%761moderatenot evaluable deaths (time to event analysis only)detailed resultsPlasmAr, 2020 0.93 [0.47; 1.85] 0.93[0.47; 1.85]PlasmAr, 202010%333lownot evaluable clinical deteriorationdetailed resultsConPlas-19, 2020 0.27 [0.06; 1.25] Libster, 2020 0.52 [0.29; 0.94] 0.48[0.28; 0.83]ConPlas-19, 2020, Libster, 202020%241moderatenot evaluable clinical improvementdetailed resultsConPlas-19, 2020 0.94 [0.59; 1.50] Li, 2015 1.40 [0.79; 2.49] PlasmAr, 2020 0.81 [0.50; 1.31] 0.99[0.73; 1.33]ConPlas-19, 2020, Li, 2015, PlasmAr, 202035%517moderatenot evaluable clinical improvement (28-day)detailed resultsLi, 2015 1.42 [0.65; 3.10] 1.42[0.65; 3.10]Li, 201510%103moderatenot evaluable ventilationdetailed resultsAlQahtani, 2020 0.67 [0.22; 2.02] 0.67[0.22; 2.02]AlQahtani, 202010%40moderatenot evaluable ICU admissiondetailed resultsLibster, 2020 0.33 [0.07; 1.58] 0.33[0.07; 1.58]Libster, 202010%160lownot evaluable serious adverse eventsdetailed resultsConPlas-19, 2020 0.96 [0.29; 3.17] PlasmAr, 2020 1.40 [0.78; 2.51] 1.30[0.77; 2.20]ConPlas-19, 2020, PlasmAr, 202020%414moderatenot evaluable0.22.01.0relative treatment effectwww.metaEvidence.org2021-01-24 07:26 +01:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 95,94,90,91 - treatments: 538 - roots T: 290