All patients
corticosteroids: no corticosteroids: yes critical disease severe disease
Immunosuppressants drugs in COVID-19 mild to moderate - Summary of results Outcome TE 95% CI n k I2 ROB Pub. bias death D28detailed results CAN-COVID, 2020 0.67 [0.30; 1.50]
CORIMUNO-ANA-1, 2021 0.91 [0.38; 2.19]
0.77 [0.43 ; 1.40 ] CAN-COVID, 2020, CORIMUNO-ANA-1, 2021 2 0% 559 moderate not evaluable deathsdetailed results CAN-COVID, 2020 0.67 [0.30; 1.50]
CORIMUNO-ANA-1, 2021 0.97 [0.46; 2.04]
LIVE-AIR (Temesgen), 2021 0.70 [0.40; 1.21]
SAVE-MORE, 2021 0.45 [0.20; 0.99]
0.68 [0.48 ; 0.97 ] CAN-COVID, 2020, CORIMUNO-ANA-1, 2021, LIVE-AIR (Temesgen), 2021, SAVE-MORE, 2021 4 0% 1,632 moderate not evaluable deaths (time to event analysis only)detailed results LIVE-AIR (Temesgen), 2021 0.70 [0.40; 1.21]
0.70 [0.40 ; 1.21 ] LIVE-AIR (Temesgen), 2021 1 0% 479 NA not evaluable clinical deteriorationdetailed results CORIMUNO-ANA-1, 2021 0.89 [0.42; 1.92]
SAVE-MORE, 2021 0.36 [0.26; 0.50]
0.53 [0.22 ; 1.28 ] CORIMUNO-ANA-1, 2021, SAVE-MORE, 2021 2 78% 114 low not evaluable clinical improvementdetailed results CAN-COVID, 2020 1.39 [0.76; 2.54]
1.39 [0.76 ; 2.54 ] CAN-COVID, 2020 1 0% 446 NA not evaluable death or ventilationdetailed results CORIMUNO-ANA-1, 2021 0.97 [0.62; 1.52]
LIVE-AIR (Temesgen), 2021 0.65 [0.43; 0.98]
0.79 [0.53 ; 1.16 ] CORIMUNO-ANA-1, 2021, LIVE-AIR (Temesgen), 2021 2 40% 116 moderate not evaluable mechanical ventilationdetailed results SAVE-MORE, 2021 0.47 [0.03; 7.48]
0.47 [0.03 ; 7.48 ] SAVE-MORE, 2021 1 0% 594 NA not evaluable serious adverse eventsdetailed results CAN-COVID, 2020 0.73 [0.45; 1.19]
0.73 [0.45 ; 1.19 ] CAN-COVID, 2020 1 0% 448 NA not evaluable 0.2 2.0 1.0 relative treatment effect www.metaEvidence.org 2025-03-09 03:14 +01:00
TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers);
k: number of studies; n: total number of patients;
ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1;
studied treatment is better when TE < 1;
pathologies: 90
- treatments: 596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526
- roots T: 290