published meta-analysis   sensitivity analysis   studies

Immunosuppressants drugs in COVID 19 all comers - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsRECOVERY, 2022 0.87 [0.77; 0.98] 0.87[0.77; 0.98]RECOVERY, 202210%8,156NAnot evaluable death or transfer to ICUdetailed resultsBACC Bay Tocilizumab Trial, 2020 0.97 [0.50; 1.88] 0.97[0.50; 1.88]BACC Bay Tocilizumab Trial, 202010%242NAnot evaluable deathsdetailed resultsBACC Bay Tocilizumab Trial, 2020 1.52 [0.41; 5.62] RECOVERY, 2022 0.87 [0.77; 0.98] 0.87[0.78; 0.99]BACC Bay Tocilizumab Trial, 2020, RECOVERY, 202220%8,398moderatenot evaluable clinical deteriorationdetailed resultsBACC Bay Tocilizumab Trial, 2020 1.11 [0.59; 2.09] 1.11[0.59; 2.09]BACC Bay Tocilizumab Trial, 202010%242NAnot evaluable clinical improvementdetailed resultsBACC Bay Tocilizumab Trial, 2020 1.06 [0.80; 1.41] 1.06[0.80; 1.41]BACC Bay Tocilizumab Trial, 202010%242NAnot evaluable death or ventilationdetailed resultsBACC Bay Tocilizumab Trial, 2020 0.83 [0.38; 1.81] RECOVERY, 2022 0.90 [0.81; 0.99] 0.90[0.81; 0.99]BACC Bay Tocilizumab Trial, 2020, RECOVERY, 202220%8,147moderatenot evaluable mechanical ventilationdetailed resultsRECOVERY, 2022 0.87 [0.74; 1.02] 0.87[0.74; 1.02]RECOVERY, 202210%7,905NAnot evaluable serious adverse eventsdetailed resultsBACC Bay Tocilizumab Trial, 2020 1.21 [0.58; 2.53] 1.21[0.58; 2.53]BACC Bay Tocilizumab Trial, 202010%242NAnot evaluable0.52.01.0relative treatment effectwww.metaEvidence.org2024-03-29 16:22 +01:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 94 - treatments: 596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526 - roots T: 290