published meta-analysis   sensitivity analysis   studies

anti-inflammatory therapies in COVID-19 (hospitalized or not) - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsAbu Esba LC (any NSAID use, acute and chronic), 2020 0.49 [0.18; 1.36] Lund, 2020 1.02 [0.57; 1.82] Manenti, 2021 0.24 [0.09; 0.65] Rinott, 2020 1.22 [0.32; 4.60] Wong (OpenSAFELY) (Study 1: General population, any NSAID), 2020 0.95 [0.80; 1.13] 0.75[0.48; 1.18]Abu Esba LC (any NSAID use, acute and chronic), 2020, Lund, 2020, Manenti, 2021, Rinott, 2020, Wong (OpenSAFELY) (Study 1: General population, any NSAID), 2020554%2,097NAnot evaluable deaths (time to event analysis only)detailed resultsManenti, 2021 0.24 [0.09; 0.65] 0.24[0.09; 0.65]Manenti, 202110%71NAnot evaluable hospitalizationdetailed resultsAbu Esba LC (any NSAID use, acute and chronic), 2020 1.54 [1.06; 2.24] Gianfransesco, 2020 0.64 [0.39; 1.06] Lund, 2020 1.16 [0.87; 1.54] 1.08[0.71; 1.65]Abu Esba LC (any NSAID use, acute and chronic), 2020, Gianfransesco, 2020, Lund, 2020374%2,064NAnot evaluable mechanical ventilationdetailed resultsAbu Esba LC (any NSAID use, acute and chronic), 2020 0.92 [0.48; 1.75] Lund, 2020 1.14 [0.56; 2.31] Rinott, 2020 0.93 [0.43; 2.01] 0.99[0.66; 1.48]Abu Esba LC (any NSAID use, acute and chronic), 2020, Lund, 2020, Rinott, 202030%2,021NAnot evaluable ICU admissiondetailed resultsLund, 2020 1.04 [0.54; 2.01] Rinott, 2020 1.42 [0.49; 4.10] 1.13[0.65; 1.99]Lund, 2020, Rinott, 202020%1,515NAnot evaluable severe COVID-19 occurrencedetailed resultsAbu Esba LC (any NSAID use, acute and chronic), 2020 0.73 [0.34; 1.56] 0.73[0.34; 1.56]Abu Esba LC (any NSAID use, acute and chronic), 202010%503NAnot evaluable0.02.01.0relative treatment effectwww.metaEvidence.org2024-05-23 16:04 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 87 - treatments: 564,944,682,1266,943,894,560,1102,598,563,668,753,752,836,639,541,534,581,615 - roots T: 290