| Study |
|
Exclusion reasons |
Remarks |
Reference(s) |
|
|
Rimland, 2020
|
single-arm
|
|
|
|
|
|
Ahn, 2020
|
-
|
|
|
Ahn J. Korean Med. Sci. 2020; 35:e149 10.3346/jkms.2020.35.e149
|
|
|
Shen, 2020
|
-
|
|
|
Shen C JAMA 2020 Mar 27;323(16):1582-1589. 10.1001/jama.2020.4783
|
|
|
BREATH-19 Study, 0
|
single-arm
|
|
|
|
|
|
Kragholm, 2020
|
population based cohort retrospective
|
|
|
Kragholm K et al. Clinical and Translational Science 10.1111/cts.12904
|
|
|
O'Brien (Part A: uninfected household contacts), 2021
|
randomized controlled trial
|
|
< Study carried out before the release of the omicron variant >
|
O'Brien MP et al. medrxiv;2021.06.14.21258569v1 10.1101/2021.06.14.21258569 O'Brien MP et al. New England Journal of Medicine 10.1056/NEJMoa2109682 O?Brien MP et al. medRxiv 10.1101/2021.06.14.21258567
|
|
|
O'Brien (Part B: recently infected asymptomatic patients), 2021
|
randomized controlled trial
|
|
|
O'Brien MP et al. medrxiv;2021.06.14.21258569v1 10.1101/2021.06.14.21258569
|
|
|
Gritti et al., 2020
|
single-arm
|
inadequate or absent control group
|
|
Gritti et al. medRxiv 10.1101/2020.04.01.20048561
|
|
|
Huijie Bian, 2020
|
non randomized controlled trial
|
not relevant study design
|
study with major methological limitations precluding any conclusion
|
Huijie Bian medRxiv 10.1101/2020.03.21.20040691
|
|
|
Yin Wang et al., 2020
|
retrospective cohort (registry)
|
not relevant study design
|
|
Yin Wang et al. medRxiv 10.1101/2020.03.06.20032342
|
|
|
Ye, 2020
|
-
|
no control group
|
|
Ye J. Med. Virol. 2020; : 10.1002/jmv.25882
|
|
|
Zhang, 2020
|
-
|
no control group
|
|
Zhang Chest 2020; : 10.1016/j.chest.2020.03.039
|
|
|
Zhang, 2020
|
-
|
no control group
|
|
Zhang L Aging (Albany NY) 2020 Apr 22;12(8):6536-6542. 10.18632/aging.103102
|
|
|
Toniati, 2020
|
observational study
|
no control group
|
|
Toniati Autoimmun Rev 2020; 19:102568 10.1016/j.autrev.2020.102568
|
|
|
Price, 2020
|
retrospective cohort
|
no control group
|
|
Price Chest 2020; : 10.1016/j.chest.2020.06.006
|
|
|
Roschewski, 2020
|
observational study
|
no control group
|
|
Roschewski M Sci Immunol 2020 Jun 5;5(48):eabd0110. 10.1126/sciimmunol.abd0110
|
|
|
CT-P59 1.2, 2020
|
randomized controlled trial
|
no clinically relevant endpoint
|
preliminary unpublished results extracted from the EMA review document. < Study carried out before the release of the omicron variant >
|
|
|
|
Yildiz, 2021
|
randomized controlled trial
|
no clinically relevant endpoint
|
|
Yildiz E Indian J Otolaryngol Head Neck Surg 2021 Jul 10;1-6. 10.1007/s12070-021-02749-9
|
|
|
Bargay-Lleonart, 2022
|
randomized controlled trial
|
no clinically relevant endpoint
|
The trial was terminated early due to the impossibility of recruitment due to the pandemic.
|
Bargay-Lleonart J J Clin Med 2022 May 27;11(11):3039. 10.3390/jcm11113039
|
|
|
Dai W, 2020
|
retrospective cohort
|
other
|
inadequate statistical analysis
|
Wei Dai, Jian Wu, Tianfu Li, Jiawei Shen, Rongrong Pang, Bangshun He, Tao Luo, Yanju Guo, Yang Yang, Jun Zhao, Mingchao Zhang, Na Li, Ying Han, Qiuyue Wu, Weiwei Li, Xinyi Xia BMC Cardiovascular Diabetology
|
|
|
Bernaola, 2020
|
retrospective cohort
|
other
|
|
Nikolas Bernaola medrxiv;2020.07.17.20155960v1 10.1101/2020.07.17.20155960
|
|
|
Holt, 2020
|
retrospective cohort
|
other
|
no CI reported
|
Holt, Gregory E 10.21203/rs.3.rs-39875/v1
|
|
|
Klopfenstein, 2020
|
retrospective cohort
|
other
|
major flaws in the method
|
Klopfenstein T International Journal of Infectious Diseases 10.1016/j.ijid.2020.08.024
|
|
|
Cantini, 2020
|
non randomized controlled trial
|
other
|
same patients than in Cantini et al. (octobre publication)
|
Cantini F J Infect 2020 Aug;81(2):318-356. 10.1016/j.jinf.2020.04.017
|
|
|
Isa, 2021
|
randomized controlled trial
|
other
|
Phase I: multiple-dose administration of REGEN-COV.
|
Isa F et al. medRxiv 10.1101/2021.11.10.21265889
|
|
