Study | Exclusion reasons | Remarks | Reference(s) | ||
---|---|---|---|---|---|
HYDRA, 2020 | randomized controlled trial | Initially found in Axfors et al. meta-analysis results published by Hernadez et al | |||
Duke university (Hydroxychloroquine), 2020 | randomized controlled trial | cancelled by investigator | |||
Duke University azithromycin, 2020 | randomized controlled trial | cancelled by investigator | Discontinuated : Poor recruitment, strong evidence from larger trials of no therapeutic benefit | ||
Erdem, 2020 | retrospective cohort (registry) | no control group | |||
Yamamura, 2020 | single-arm | no control group |
Yamamura H Crit Care 2020 Jul 9;24(1):413. 10.1186/s13054-020-03137-5 |
||
Murohashi, 2020 | prospective cohort | no control group |
Murohashi K Respir Investig 2020 Aug 28;58(6):430-434. 10.1016/j.resinv.2020.08.001 |
||
SIMPLE (Grein), 0 | single-arm | no control group | single-arm with external control group |
Grein N. Engl. J. Med. 2020; 382:2327-2336 10.1056/NEJMoa2007016 |
|
Niaee (vs placebo), 2020 | randomized controlled trial | other | On 8 October 2021 and 9 October 2021, two articles were published by subject-matter experts outlining concerns about various aspects of the study and, in particular, calling into question the randomization of participants. The authors and publishing journal have been alerted to these issues, and this note will be updated with any new information related to the publication. |
Niaee MS et al. researchsquare 10.21203/rs.3.rs-109670/v1 Niaee MS et al. Asian Pacific Journal of Tropical Medicine 10.4103/1995-7645.318304 |