antiviral and associated therapy living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only

	COVID-19 severe or critically

	COVID-19 prophylaxis (excluding children)
antiviral and associated therapy
bromhexine	Mikhaylov
chloroquine and derivatives
hydroxychloroquine	Barnabas RV Grau-Pujol COVID PREP ... COVID PREP HCQ ... HERO-HCQ ... PATCH-cohort 3 PreP ... Abella Syed COVID-PEP-Post exposure ... BCN PEP-CoV-2-Study 1 ... EPICOS ... Rojas-Serrano Seet ...
ivermectin	Seet 2021 Ivercar-Tuc NCT04422561 ...
nirmatrelvir / ritonavir (Paxlovid)	EPIC PEP

5448	COVID-19 Global Rheumatology Alliance, 2020	0	13	0	selection pending
6372	Alam, 2020	0	31	3	selection pending
6373	Behera, 2020	1	20	0		not a RCT	risk of bias not avaialble
6374	NCT04425850 (Caravallo), 2020	2	31	0	excluded	not a RCT	risk of bias not avaialble
8328	Behera, 2021	0	13	0	selection pending