potential COVID-19 treatments living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only

	COVID-19 severe or critically

	COVID 19 outpatients
potential COVID-19 treatments
adjuvant therapies
febuxostat	Davoodi
anti-inflammatoty and immuno-therapy
anti-inflammatory therapies
colchicine	PRINCIPLE ... COLCORONA
corticosteroids
ciclesonide	Clemency Ezer N ...
Immunostimulants drugs
convalescent plasma treatment	CONV-ERT C3PO CoV-Early ...
Early convalescent plasma.	CoV-Early ...
interferon
inhaled interferon
SNG001 inhaled interferon beta	ACTIV-2 SNG001
peginterferon	TOGETHER interferon lambda Feld
neutralizing antibody
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences)	ACTIV-2 ...
bamlanivimab monotherapy	OPTIMISE-C19 ... BLAZE-1 phase 2 ...
bamlanivimab/etesevimab	BLAZE-1 phase 2 ... BLAZE-1 phase 3 ... BLAZE-4 OPTIMISE-C19 ...
Bebtelovimab (LY-CoV1404)	BLAZE 4 LY-CoV1404
casirivimab/imdevimab (Ronapreve)	Cov-2067 Weinreich ... Cov-2069 ... Mazzotta
cilgavimab and tixagevimab (Evusheld)	TACKLE
regdanvimab (Regkirona- CT-P59-Celltrion)	CT-P59 3.2 part 1 CT-P59 3.2 part 2
sotrovimab (Xevudy; VIR-7831)	COMET-ICE
inhaled corticosteroids
budesonide	PRINCIPLE STOIC
antiandrogenic
dutasteride	Cadegiani ...
antiviral and associated therapy
azithromycin	ACTION PRINCIPLE Hinks ...
chloroquine and derivatives	ALBERTA HOPE-Covid19
hydroxychloroquine	NCT04597775 COPE – Coalition V COVID-PEP Severity ... BCN PEP-CoV-2-Study 2 ... PATCH Cohort 1 ... Reis ... Q-PROTECT -HCQ alone COMIHY
fluvoxamine	COVID-OUT ... Lenze ... TOGETHER ACTIV-6
hydroxychloroquine plus macrolides	NCT04621461
azithromycin plus hydroxychloroquine	Q-PROTECT -AZI ... Rodrigues Q-PROTECT ...
ivermectin	ACTIV-6 ... IVERCORCOVID19 ... Chaccour ACTIV 6 ivermectin Buonfrate ... Chahla COVID-OUT ... Lopez-Medina TOGETHER ... Podder
ivermectin plus doxycycline	Chowdhury A
lopinavir/ritonavir	Reis ...
molnupiravir	MOVe-OUT Fischer ...
nirmatrelvir / ritonavir (Paxlovid)	EPIC-HR
nitazoxanide	RM08-3008 ...
remdesivir	PINETREE ...
sofosbuvir and daclatasvir	Roozbeh
umifenovir (arbidol)	Ramachandran
zinc	Thomas ...
Oral antidiabetic drugs
metformin	TOGETHER COVID-OUT ...
Renin-angiotensin-system-acting agents
angiotensin receptor blockers (ARBs)	University of Minnesota
discontinuation of ACEI/ARB	ACEI-COVID ...
Vitamins
vitamin C	Thomas ...
zinc plus vitamin c	Thomas ...

0 studies excluded by filtering options 1