chloroquine and derivatives living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only observational study

	COVID 19 hospitalized
	COVID-19 mild to moderate
chloroquine and derivatives
chloroquine	NCT04342650
hydroxychloroquine	Coalition Covid-19 Brazil I ... Min NCT04333654 FACCT Trial Dubee HC-nCoV ... Kamran Zhaowei Chen

4899	ChiCTR2000029826 (Cancelled by the investigator), 0	2	1	0	excluded		risk of bias not avaialble
4905	ChiCTR2000029975, 0	2	30	0	excluded	not a RCT	risk of bias not avaialble
4987	CloroCOVID19, 2020	2	1	3	excluded		high risk of bias
5226	Duke university (Hydroxychloroquine), 2020	2	1	0	excluded		risk of bias not avaialble
5288	Barbosa, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
5300	Raquel, 2019	2	1	0	excluded		risk of bias not avaialble
5303	Jacobson, 2016	2	1	0	excluded		risk of bias not avaialble
5308	Sperber, 1995	2	1	0	excluded		risk of bias not avaialble
5309	Paton, 2012	2	1	0	excluded		risk of bias not avaialble
5351	Mallat, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
5374	Million, 2020	2	30	0	excluded	not a RCT	risk of bias not avaialble
5375	Mehra, 2020	2	13	3	excluded	not a RCT	high risk of bias
5416	Guerin, 2020	2	31	4	excluded	not a RCT	high risk of bias
5560	BCN PEP-CoV-2-Study 2 (Mitja Lancet-preprint), 2020	2	1	2	excluded
5564	Kanran M, 2020	2	1	0	excluded		risk of bias not avaialble
5776	Alberici, 2020	2	13	4	excluded	not a RCT	high risk of bias
5864	HYDRA, 2020	2	1	0	excluded		risk of bias not avaialble
6032	Mohana, 2020	2	12	0	excluded	not a RCT	risk of bias not avaialble
6697	Thakar, 2021	2	1	0	excluded		risk of bias not avaialble
6910	Thakar, 2021	2	1	0	excluded		risk of bias not avaialble