antiviral and associated therapy living meta-analysis of clinical studies

table network network 2

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only observational study

39 studies excluded by filtering options 2

4899	ChiCTR2000029826 (Cancelled by the investigator), 0	2	1	0	excluded		risk of bias not avaialble
4905	ChiCTR2000029975, 0	2	30	0	excluded	not a RCT	risk of bias not avaialble
4987	CloroCOVID19, 2020	2	1	3	excluded		high risk of bias
5209	SIMPLE (Grein), 0	2	30	0	excluded	not a RCT	risk of bias not avaialble
5210	Ye et al., 2020	2	99	0	excluded	not a RCT	risk of bias not avaialble
5226	Duke university (Hydroxychloroquine), 2020	2	1	0	excluded		risk of bias not avaialble
5259	Duke University azithromycin, 2020	2	1	0	excluded		risk of bias not avaialble
5288	Barbosa, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
5300	Raquel, 2019	2	1	0	excluded		risk of bias not avaialble
5303	Jacobson, 2016	2	1	0	excluded		risk of bias not avaialble
5308	Sperber, 1995	2	1	0	excluded		risk of bias not avaialble
5309	Paton, 2012	2	1	0	excluded		risk of bias not avaialble
5351	Mallat, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
5374	Million, 2020	2	30	0	excluded	not a RCT	risk of bias not avaialble
5375	Mehra, 2020	2	13	3	excluded	not a RCT	high risk of bias
5375	Mehra, 2020	2	13	3	excluded	not a RCT	high risk of bias
5416	Guerin, 2020	2	31	4	excluded	not a RCT	high risk of bias
5416	Guerin, 2020	2	31	4	excluded	not a RCT	high risk of bias
5521	Del Amo, 2020	2	0	0	excluded		risk of bias not avaialble
6080	IDEA, 2020	2	10	0	excluded	not a RCT	risk of bias not avaialble
6083	IFORS (Pott-Junior), 2020	2	1	3	excluded		high risk of bias
6096	Elgazzar - treatment, 2020	2	1	3	excluded		high risk of bias
6097	Elgazzar - prophylaxis, 2020	2	1	3	excluded		high risk of bias
6098	Patel, 2020	2	10	0	excluded	not a RCT	risk of bias not avaialble
6134	Morgenstern, 2020	2	30	0	excluded	not a RCT	risk of bias not avaialble
6184	Erdem, 2020	2	11	0	excluded	not a RCT	risk of bias not avaialble
6262	Yamamura, 2020	2	30	0	excluded	not a RCT	risk of bias not avaialble
6267	Murohashi, 2020	2	10	0	excluded	not a RCT	risk of bias not avaialble
6339	Delliere, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
6368	Niaee (vs placebo), 2020	2	1	3	excluded		high risk of bias
6374	NCT04425850 (Caravallo), 2020	2	31	0	excluded	not a RCT	risk of bias not avaialble
6375	Cadegiani -Iver, 2020	2	99	0	excluded	not a RCT	risk of bias not avaialble
6379	Chamie-Quintero,, 2020	2	15	0	excluded	not a RCT	risk of bias not avaialble
6526	Dabbous, 2021	2	1	3	excluded		high risk of bias
6625	Nasir, 2020	2	31	0	excluded	not a RCT	risk of bias not avaialble
6625	Nasir, 2020	2	31	0	excluded	not a RCT	risk of bias not avaialble
7314	Samaha, 2021	2	1	3	excluded		high risk of bias
7995	Hazan, 2021	2	32	0	excluded	not a RCT	risk of bias not avaialble
10322	Elgazzar, 0	2	0	0	excluded		risk of bias not avaialble

	COVID 19 hospitalized
	COVID 19 all comers
antiviral and associated therapy
chloroquine and derivatives
chloroquine	Chen, ChiCTR2000030054 - Chloroquine
hydroxychloroquine	NCT04376814-Group A Gautret et al. NCT04376814-Group A ChiCTR2000030054-HCQ ... IRCT20150808023559N20 NOR-Solidarity ... IRCT20150808023559N20
darunavir cobicistat	Jun C
favipiravir	Cai -FAVIPIRAVIR jRCTs041190120 Lou ... NCT04376814-Group A IRCT20150808023559N20 Calik Chang Chen et al. NCT04310228-FAVI ... IRCT20150808023559N20 Cai -FAVIPIRAVIR NCT04376814-Group A
hydroxychloroquine plus macrolides	Magagnoli ...
nirmatrelvir / ritonavir (Paxlovid)	EPIC-SR
remdesivir	Andreas ... Norwegian NOR study ...
umifenovir (arbidol)	ELACOI ...