| 4899 | ChiCTR2000029826 (Cancelled by the investigator), 0 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 4905 | ChiCTR2000029975, 0 | 2 | 30 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 4987 | CloroCOVID19, 2020 | 2 | 1 | 3 | excluded | high risk of bias | |
| 5209 | SIMPLE (Grein), 0 | 2 | 30 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5210 | Ye et al., 2020 | 2 | 99 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5226 | Duke university (Hydroxychloroquine), 2020 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5259 | Duke University azithromycin, 2020 | 2 | 1 | 0 | excluded | risk of bias not avaialble | |
| 5288 | Barbosa, 2020 | 2 | 13 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5351 | Mallat, 2020 | 2 | 13 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 5375 | Mehra, 2020 | 2 | 13 | 3 | excluded | not a RCT | high risk of bias |
| 5375 | Mehra, 2020 | 2 | 13 | 3 | excluded | not a RCT | high risk of bias |
| 6083 | IFORS (Pott-Junior), 2020 | 2 | 1 | 3 | excluded | high risk of bias | |
| 6096 | Elgazzar - treatment, 2020 | 2 | 1 | 3 | excluded | high risk of bias | |
| 6184 | Erdem, 2020 | 2 | 11 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 6262 | Yamamura, 2020 | 2 | 30 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 6267 | Murohashi, 2020 | 2 | 10 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 6368 | Niaee (vs placebo), 2020 | 2 | 1 | 3 | excluded | high risk of bias | |
| 6375 | Cadegiani -Iver, 2020 | 2 | 99 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 6526 | Dabbous, 2021 | 2 | 1 | 3 | excluded | high risk of bias | |
| 6625 | Nasir, 2020 | 2 | 31 | 0 | excluded | not a RCT | risk of bias not avaialble |
| 7995 | Hazan, 2021 | 2 | 32 | 0 | excluded | not a RCT | risk of bias not avaialble |
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