potential COVID-19 treatments living meta-analysis of clinical studies

	COVID 19 all comers	COVID-19 mild to moderate

	COVID 19 hospitalized	COVID 19 all comers	COVID-19 mild to moderate
potential COVID-19 treatments
adjuvant therapies
anticoagulant	Paranjpe		X-COVID-19
anticoagulant, curative dose	Bousquet Bousquet COALIZAO ACTION		ATTACC, ACTIV-4a, and REMAP-CAP ...
anticoagulant, prophylactic dose	Bousquet Bousquet
heparin at therapeutic dose			RAPID ...
anti-inflammatoty and immuno-therapy
anti-inflammatory therapies	Malgorzata
anti GM-CSF
mavrilimumab	MASH-COVID ...
clarithromycine	Tsiakos		Rashad ...
colchicine	COLCOVID Scarsi Lopes MIF Salehzadeh GRECCO-19 RECOVERY ... Horby Sandhu		COL-COVID ...
Colchicine plus rosuvastatin	COLSTAT Gaitan-Duarte ...
non-steroidal anti-inflammatory drugs	Jeong Bruce Imam Drake		Guzman-Esquivel
Celecoxib	Wenxin
Indomethacin			Ravichandran Ravichandran
stem cells	Lanzoni Carmenate ...
corticosteroids	Fernández Cruz GLUCOCOVID Rahman Albani SAM-COVID-19 Rodriguez-Bano ... Rodriguez-Bano ...		Li ... Majmundar
dexamethasone	RECOVERY dexamethasone
methylprednisolone	Tang X Metcovid Ranjbar
Immunostimulants drugs
convalescent plasma treatment	ConCOVID ... Abolghasemi Salazar ConPlas-19 COP-COVID-19 CONTAIN COVID-19 PC/COVID-19 NCT04397757 PLACO-COVID CONCOR-1 CPC-SARS NCT04442191 DAWN-Plasma NCT04385199 COPLA-II trial NCT04403477 ... ASCOT RECOVERY ... CONFIDENT PERUCONPLASMA Bennett-Guerrero Salman Kirenga LACCPT Co-CLARITY NCT04528368 Holm K CCAP-2 Baldeon Menichetti	LIFESAVER	PLACID Libster
Early convalescent plasma.	Balcells
immunoglobulin therapy	Sakoulas Parikh
interferon	Wang ... Wang	Cai -FAVIPIRAVIR Cai -FAVIPIRAVIR
IFN beta-1a	SOLIDARITY ...
high-dose IFN beta-1a	Darazam
IFN gamma	Esquivel-Moynelo
inhaled interferon
IFN alpha
pegylated interferon-α2b			Pandit Shashi Bhushan
recombinant super-compound interferon rSIFN-co	Li
SNG001 inhaled interferon beta	Synairgen SG016 SPRINTER
interferon / TFF2			Fu
peginterferon			Jagannathan
PNB001			Lattmann
neutralizing antibody	ITAC
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences)	ACTIV-3 ...
bamlanivimab monotherapy	ACTIV-3/TICO LY-CoV555
casirivimab/imdevimab (Ronapreve)	RECOVERY ...		Somersan-Karakaya ... Suzuki
cilgavimab and tixagevimab (Evusheld)	ACTIV-3/TICO ...	Chen
sotrovimab (Xevudy; VIR-7831)	ACTIV-3/ TICO ...
Immunosuppressants drugs
anakinra	SAVE-MORE		CORIMUNO-ANA-1
anti-interleukin-6
sarilumab	CORIMUNO-SARI-1 ...
sarilumab high dose (400mg)		sarilumab phase 2 high dose
sarilumab low dose (200mg)		sarimulab phase 2 low dose
tocilizumab	Dongsheng Wang RCT-TCZ-COVID-19 Martinez-Sanz HNF Hospital Tocilizumab multidisciplinary team Colaneri EMPACTA Tsai SAM-COVID-19 RECOVERY Soin AS ... Rutgers NCT04412772 ... Declercq J ... NCT04577534 ... EU-CTR2020-001375-32 ... EU-CTR2020-001748-24 ... NCT04479358 ... NCT04434717 ...	TOCOVID BACC Bay Tocilizumab Trial	Capra
canakinumab	Sheng ...
janus kinase (JAK) inhibitor
baricitinib	COV-BARRIER ACTT-2 ...	RECOVERY	Rodriguez-Garcia Cantini
tofacitinib	STOP-COVID ...		Murugesan
lenzilumab			LIVE-AIR ...
Kinase inhibitors
acalabrutinib	CALAVI CALAVI US
imatinib			Covid-19 HUF
leflunomide	Wang et al.	Wang
antiandrogenic
progesterone			Ghandehari
proxalutamide	Cadegiani
antiviral and associated therapy
azithromycin	Rosenberg Sekhavati Rodriguez-Molinero RECOVERY ...		COALITION I Covid-19 Brazil ... Espitia-Hernandez Rashad A ...
azvudine			Ren
baloxavir marboxil	Lou Y
bromhexine	Ansarin Tolouian		Li T
chloroquine and derivatives	Rosenberg
chloroquine	Chen_chloroquine Huang Huang	Chen, ChiCTR2000030054 - Chloroquine	NCT04342650
hydroxychloroquine	Tang HAHPS ORCHID Duke University hydroxychloroquine/azithromycine Magagnoli ... Geleris Novales RECOVERY Paccoud Sbidian ... SOLIDARITY ... Arshad ... Chen NO COVID-19 ... Kalligeros Belgian Collaborative Group on COVID-19 Abd-Elsalam Cravedi Fontana Singh CCAP-1 Duke university HCQ ARCHAIC -hydroxychloroquine PROTECT B TEACH OAHU-COVID19 HYCOVID IRCT20200428047228N1 // U07 Gonzalez ... PROTECT A	Gautret et al. ChiCTR2000030054-HCQ ... IRCT20150808023559N20 IRCT20150808023559N20 NCT04376814-Group A NCT04376814-Group A NOR-Solidarity ...	HC-nCoV ... Zhaowei Chen Coalition Covid-19 Brazil I ... Min NCT04333654 FACCT Trial Dubee Kamran
darunavir cobicistat		Jun C
doxycycline	Spoorthi		Spoorthi
Emtricitabine/tenofovir plus colchicine plus rosuvastatin	Gaitan-Duarte ...
Ensitrelvir (XOCOVA)			Mukae - Phase 2a
favipiravir	IRCT20200428047228N1 // U07 Udwadia AVIFAVIR	Cai -FAVIPIRAVIR Cai -FAVIPIRAVIR Lou ... Chang Chen et al. NCT04310228-FAVI ... jRCTs041190120 IRCT20150808023559N20 IRCT20150808023559N20 NCT04376814-Group A NCT04376814-Group A Calik	Dabbous HM Holubar M IRCT20151227025726N14 // U07 FACCT Trial Udwadia AVIFAVIR Shenoy S NCT04542694 Ruzhentsova T Solaymani-Dodaran Shinkai
favipiravir plus interferon			Khamis
hydroxychloroquine plus macrolides	Rosenberg Carlucci Sbidian ... Lagier Arshad ... Davido Duke university HCQ-AZI	Magagnoli ...
azithromycin plus hydroxychloroquine	ProPAC-COVID		Coalition Covid-19 Brazil I ...
ivermectin	ICON Khan Soto-Becerra Spoorthi Gonzalez ...		Glorial F Shahbaznejad Ahmed Chachar Chaccour Espitia-Hernandez Khan Soto-Becerra Spoorthi Bukhari Kirti Babalola RIVET-COV ... Abd-Elsalam Krolewiecki I-TECH ... Mayer
ivermectin plus doxycycline	Hashim A		NCT04523831 ...
lopinavir/ritonavir	RECOVERY SOLIDARITY ... Nojomi Chen_lopi_rito Ader ...		ELACOI ...
lopinavir/ritonavir plus interferon ß-1a	Ader ...
lopinavir/ritonavir, ribavirin and interferon beta-1b			Hung et al.
niclosamide	Abdulamir
nirmatrelvir / ritonavir (Paxlovid)		EPIC-SR
nitazoxanide			Rocco Silva Fontanesi
opaganib	Winthrop
oseltamivir	Chen_oseltamivir
remdesivir	NIH NIAID ACTT-1 DisCoVeRy ... remdesevir external control SOLIDARITY ... Mahajan	Norwegian NOR study ... Andreas ...	GS-US-540-5774, 10 days GS-US-540-5774, 5 days GS-US-540-5773 ...
sofosbuvir	Sali Alavi-moghaddam
sofosbuvir and daclatasvir	Sadeghi Yakoot Mobarak S ... Mobarak ...
sofosbuvir and ledipasvir	Elgohary		Nourian A
tenofovir/emtricitabine	Gaitan-Duarte ...
umifenovir (arbidol)	UAIIC Nojomi Chen_arbidol	ELACOI ...	Yethindra ELACOI ...
zinc	Patel
Drugs for acid related disorders
H2 blockers
famotidine	Samimagham
proton pump inhibitors (PPI)	Argenziano Ramachandran Zhang
miscellaneous
Aspirin	RECOVERY ...
aviptadil		COVID-AIV
camostat mesilate		Gunst JD
Cannabidiol			Crippa ...
honey	Silveira
povidone-iodine	Mohamed
sabizabulin			VERU-111
Oral antidiabetic drugs
dapagliflozin	DARE-19
DPP-4 inhibitor	CORONADO Guardado-Mendoza	Rhee ... Noh Rhee ...
Renin-angiotensin-system-acting agents		Yang Bean Zhang Li Meng Yan et al.
angiotensin receptor blockers (ARBs)	Duarte Nouri-Vaskeh
losartan		University of Minnesota
discontinuation of ACEI/ARB	REPLACE Najmeddin		Lopes ...
Vitamins
Vitamin D	Entrenas ... Murai Annweiler ... Annweiler ...		Rastogi Espitia-Hernandez
hight dose vitamin D			COVIT-TRIAL

0 studies excluded by filtering options 2