Meta-analysis results for all treatments

Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method

Treament Trials      
clinical deteriorationclinical improvementdeathsviral clearance
favipiravir 6- 1.25 [0.21; 7.62], 1 RCT, I2=0%
inconclusive result
1.12 [0.02; 62.74], 1 RCT, I2=0%
inconclusive result
0.98 [0.21; 4.57], 2 RCTs, I2=32%
inconclusive result
chloroquine and derivatives3-- 0.66 [0.04; 11.04], 2 RCTs, I2=0%
inconclusive result
OBS 16.33 [2.80; 95.27], 1 study, I2=0%
unassessable degree of certainty
remdesivir2- 1.29 [1.12; 1.49], 1 RCT, I2=0%
unassessable degree of certainty
0.55 [0.36; 0.84], 1 RCT, I2=0%
unassessable degree of certainty
-
darunavir cobicistat1 2.07 [0.06; 66.79], 1 RCT, I2=0%
inconclusive result
- 1.00 [0.02; 53.89], 1 RCT, I2=0%
inconclusive result
0.82 [0.36; 1.87], 1 RCT, I2=0%
inconclusive result
hydroxychloroquine plus macrolides1-- OBS 1.14 [0.56; 2.32], 1 study, I2=0%
inconclusive result
-
nirmatrelvir / ritonavir (Paxlovid)1----
umifenovir (arbidol)1----
Amantadine0----
ASC09/ritonavir0----
azithromycin0----
azvudine0----
baloxavir marboxil0----
bromhexine0----
carrimycin0----
danoprevir / ritonavir0----
doxycycline0----
Emtricitabine/tenofovir plus colchicine plus rosuvastatin0----
Ensitrelvir (XOCOVA)0----
favipiravir plus interferon0----
fluvoxamine0----
Interferon plus lopinavir/ritonavir0----
ivermectin0----
leronlimab0----
lopinavir / ritonavir plus ribavirin0----
lopinavir/ritonavir0----
lopinavir/ritonavir plus chloroquine0----
Lopinavir/ritonavir plus hydroxychloroquine0----
lopinavir/ritonavir plus interferon ß-1a0----
lopinavir/ritonavir, ribavirin and interferon beta-1b0----
molnupiravir0----
niclosamide0----
nitazoxanide0----
opaganib0----
oseltamivir0----
oseltamivir plus chloroquin0----
ribavirin0----
ritonavir0----
sofosbuvir0----
sofosbuvir and daclatasvir0----
sofosbuvir and ledipasvir0----
tenofovir/emtricitabine0----
tenofovir/emtricitabine plus hydroxychloroquine0----
tranexamic acid0----
tranilast0----
triazavirin0----
zinc0----