Meta-analysis results for all treatments

Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method

Treament Trials      
clinical deteriorationclinical improvementdeathsviral clearance
Immunostimulants drugs7 0.72 [0.37; 1.43], 2 RCTs, I2=58% demonstrated
inconclusive result
0.68 [0.21; 2.20], 1 RCT, I2=0%
inconclusive result
0.78 [0.58; 1.05], 6 RCTs, I2=0%
inconclusive result
1.61 [0.61; 4.25], 3 RCTs, I2=82%
inconclusive result
Immunosuppressants drugs6 0.53 [0.22; 1.28], 2 RCTs, I2=78% demonstrated
inconclusive result
1.39 [0.76; 2.54], 1 RCT, I2=0%
inconclusive result
0.68 [0.48; 0.97], 5 RCTs, I2=0%
moderate degree of certainty
-
anti-inflammatory therapies4 0.12 [0.01; 1.91], 2 RCTs, I2=69%
inconclusive result
- 0.42 [0.04; 4.91], 2 RCTs, I2=0%
inconclusive result
1.71 [0.80; 3.64], 1 RCT, I2=0%
inconclusive result
Kinase inhibitors1----
Apilimod0----
corticosteroids0----
inhaled corticosteroids0----
leflunomide0----
meplazumab0----
pirfenidone0----
Polyinosinic-Polycytidylic Acid0----
sargramostim0----
statins0----
thymosin0----