Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method
| Treament | Trials | |||||
|---|---|---|---|---|---|---|
| Demonstrated or suggested benefit | Inconclusive results | Uncertain results | Safety results | |||
| anti-inflammatory therapies | none | inconclusive results for: death D28; deaths; deaths (time to event analysis only); hospitalization; mechanical ventilation; mechanical ventilation (time to event analysis only); ICU admission; severe COVID-19 occurrence | - | - | ||
| corticosteroids | none | - | - | - | ||
| Immunostimulants drugs | none | - | suggested 61 % decrease in hospitalization or death but the degree if certainty is unassessable suggested 61 % decrease in hospitalization but the degree if certainty is unassessable | - | ||
| Immunosuppressants drugs | none | inconclusive results for: radiologic improvement (14-day); serious adverse events | - | - | ||
| Apilimod | 0 | - | - | - | - | |
| inhaled corticosteroids | 0 | - | - | - | - | |
| Kinase inhibitors | 0 | - | - | - | - | |
| leflunomide | 0 | - | - | - | - | |
| meplazumab | 0 | - | - | - | - | |
| pirfenidone | 0 | - | - | - | - | |
| Polyinosinic-Polycytidylic Acid | 0 | - | - | - | - | |
| sargramostim | 0 | - | - | - | - | |
| statins | 0 | - | - | - | - | |
| thymosin | 0 | - | - | - | - | |
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