benefit
(statisticaly significant)
benefit (nominaly significant, not statitically demonstrated) NS not significant harm statitically significant NS harm not significant low certainty due to bias
 
DOR

KRAS gene alteration defined cancer KRAS gene alteration defined cancer

NTRK gene alteration NTRK gene alteration

RET gene alteration defined cancer RET gene alteration defined cancer

versus no control (uncontrolled study)
pralsetinib vs. no control (uncontrolled study) 1 -
selpercatinib vs. no control (uncontrolled study) 1 -