button bars forest bayes pooled summary circles
 
deaths (OS)progression or deaths (PFS)RFS/DFS

mGC or mGEJC - L1 - HER2 neg/PDL1 positive metastatic/advanced mGC or mGEJC mGC or mGEJC - 1st line (L1) mGC or mGEJC - L1 - HER2 neg/PDL1 positive

versus Standard of Care (SoC)
nivolumab plus SoC vs. Standard of Care (SoC) 2 1.0better0.35.0100 %1.0better0.35.0100 %-

mGC or mGEJC - L1 - HER2 negative metastatic/advanced mGC or mGEJC mGC or mGEJC - 1st line (L1) mGC or mGEJC - L1 - HER2 negative

versus Standard of Care (SoC)
nivolumab plus SoC vs. Standard of Care (SoC) 1 1.0better0.35.0100 %1.0better0.35.0100 %-

mGC or mGEJC - L1 - PDL1 positive metastatic/advanced mGC or mGEJC mGC or mGEJC - 1st line (L1) mGC or mGEJC - L1 - PDL1 positive

versus placebo plus SoC
pembrolizumab alone vs. placebo plus SoC 1 1.0better0.35.098 %1.0better0.35.072 %-
pembrolizumab plus SoC vs. placebo plus SoC 2 1.0better0.35.095 %1.0better0.35.097 %-
versus Standard of Care (SoC)
pembrolizumab alone vs. Standard of Care (SoC) 1 1.0better0.35.082 %1.0better0.35.0100 %-

mGC or mGEJC - L2 - all population metastatic/advanced mGC or mGEJC mGC or mGEJC - 2nd Line (L2) mGC or mGEJC - L2 - all population

versus paclitaxel
avelumab alone vs. paclitaxel 1 1.0better0.35.080 %1.0better0.35.0100 %-
pembrolizumab alone vs. paclitaxel 1 1.0better0.35.076 %1.0better0.35.0100 %-
versus placebo
nivolumab alone vs. placebo 1 1.0better0.35.0100 %1.0better0.35.0100 %-
versus Standard of Care (SoC)
Ipilimumab (10 mg/kg) vs. Standard of Care (SoC) 1 1.0better0.35.087 %1.0better0.35.0100 %-

mGC or mGEJC - L2 - PDL1 positive metastatic/advanced mGC or mGEJC mGC or mGEJC - 2nd Line (L2) mGC or mGEJC - L2 - PDL1 positive

versus paclitaxel
pembrolizumab alone vs. paclitaxel 1 1.0better0.35.096 %1.0better0.35.099 %-

mGC or mGEJC - M - HER2 negative metastatic/advanced mGC or mGEJC mGC or mGEJC - maintenance (M) mGC or mGEJC - M - HER2 negative

versus Standard of Care (SoC)
avelumab alone vs. Standard of Care (SoC) 1 1.0better0.35.082 %1.0better0.35.065 %-

mGC or mGEJC - M - HER2 neg/PDL1 positive metastatic/advanced mGC or mGEJC mGC or mGEJC - maintenance (M) mGC or mGEJC - M - HER2 neg/PDL1 positive

versus Standard of Care (SoC)
avelumab alone vs. Standard of Care (SoC) 1 1.0better0.35.064 %1.0better0.35.055 %-

 

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