deaths (OS)progression or deaths (PFS)RFS/DFS

mNSCLC - L1 - PDL1 positive metastatic/advanced NSCLC (mNSCLC) - 1st line (L1) mNSCLC - L1 - PDL1 positive

versus Standard of Care (SoC)
atezolizumab alone vs. Standard of Care (SoC) 3 0.83 [0.65; 1.06], 1 RCT, I2=0%
inconclusive result
0.77 [0.63; 0.94], 1 RCT, I2=0%
unassessable degree of certainty
-
cemiplimab vs. Standard of Care (SoC) 1 0.57 [0.42; 0.77], 1 RCT, I2=0%
unassessable degree of certainty
0.54 [0.43; 0.68], 1 RCT, I2=0%
unassessable degree of certainty
-
durvalumab alone vs. Standard of Care (SoC) 1 0.76 [0.56; 1.03], 1 RCT, I2=0%
inconclusive result
0.87 [0.59; 1.29], 1 RCT, I2=0%
inconclusive result
-
nivolumab alone vs. Standard of Care (SoC) 2 1.07 [0.86; 1.33], 1 RCT, I2=0%
inconclusive result
1.17 [0.95; 1.44], 1 RCT, I2=0%
inconclusive result
-
pembrolizumab alone vs. Standard of Care (SoC) 4 0.74 [0.56; 0.97], 2 RCTs, I2=51% conclusive
moderate degree of certainty
0.74 [0.35; 1.56], 2 RCTs, I2=95%
inconclusive result
-