deaths (OS)progression or deaths (PFS)RFS/DFS

mML - NA - all population metastatic/adv melanoma (mML) mML - (neo)adjuvant (NA) mML - NA - all population

versus interferon alpha
Ipilimumab (10 mg/kg) vs. interferon alpha 1 certainty unassessable-11%- certainty unassessable-15%
ipilimumab alone vs. interferon alpha 1 low degree of certaintystatistically conclusive-16%- low degree of certainty-14%
versus Ipilimumab (10 mg/kg)
nivolumab alone vs. Ipilimumab (10 mg/kg) 1 certainty unassessable-12%- certainty unassessablestatistically conclusive-32%
versus nivolumab alone
nivolumab plus ipilimumab vs. nivolumab alone 1 -- certainty unassessable-55%
versus placebo
Ipilimumab (10 mg/kg) vs. placebo 1 certainty unassessablestatistically conclusive-26%- certainty unassessablestatistically conclusive-23%
nivolumab alone vs. placebo 1 -- certainty unassessablestatistically conclusive-40%
nivolumab plus ipilimumab vs. placebo 1 -- certainty unassessablestatistically conclusive-71%
pembrolizumab alone vs. placebo 1 -- certainty unassessablestatistically conclusive-40%