deaths (OS)progression or deaths (PFS)RFS/DFS

mML - L2 - all population metastatic/adv melanoma (mML) mML - 2nd line (L2) mML - L2 - all population

versus gp100
ipilimumab alone vs. gp100 1 certainty unassessablestatistically conclusive-31%--
ipilimumab plus gp100 vs. gp100 1 certainty unassessablestatistically conclusive-29%--
versus ipilimumab alone
Ipilimumab (10 mg/kg) vs. ipilimumab alone 1 certainty unassessablestatistically conclusive-15% certainty unassessable-10%-
ipilimumab plus gp100 vs. ipilimumab alone 1 certainty unassessable+4%--
pembrolizumab (10mg/kg) vs. ipilimumab alone 1 certainty unassessablestatistically conclusive-29% certainty unassessablestatistically conclusive-39%-
pembrolizumab (10mg/kg) 2 weeks vs. ipilimumab alone 1 certainty unassessablestatistically conclusive-34% certainty unassessablestatistically conclusive-39%-
versus placebo plus SoC
ipilimumab plus SoC vs. placebo plus SoC 1 certainty unassessablestatistically conclusive-26% certainty unassessablestatistically conclusive-22%-
versus Standard of Care (SoC)
nivolumab alone vs. Standard of Care (SoC) 1 certainty unassessable-5% certainty unassessable+3%-
pembrolizumab (10mg/kg) vs. Standard of Care (SoC) 1 certainty unassessable-24% certainty unassessablestatistically conclusive-46%-
pembrolizumab (2mg/kg) vs. Standard of Care (SoC) 1 certainty unassessable-13% certainty unassessablestatistically conclusive-40%-