DCR

mML - L1 - all population metastatic/adv melanoma (mML) mML - 1st line (L1) mML - L1 - all population

versus ipilimumab alone
nivolumab alone vs. ipilimumab alone 1 -
nivolumab plus ipilimumab vs. ipilimumab alone 2 -
versus ipilimumab followed by nivolumab
nivolumab followed by ipilimumab vs. ipilimumab followed by nivolumab 1 -
versus nivolumab alone
nivolumab plus ipilimumab vs. nivolumab alone 1 -
relatlimab plus nivolumab vs. nivolumab alone 1 -
versus Standard of Care (SoC)
tremelimumab vs. Standard of Care (SoC) 1 -

mML - L1 - BRAF mutant metastatic/adv melanoma (mML) mML - 1st line (L1) mML - L1 - BRAF mutant

versus ipilimumab alone
nivolumab plus ipilimumab vs. ipilimumab alone 1 -
versus placebo plus SoC
atezolizumab plus SoC vs. placebo plus SoC 1 -

mML - L1 - BRAF wild metastatic/adv melanoma (mML) mML - 1st line (L1) mML - L1 - BRAF wild

versus dacarbazine
nivolumab alone vs. dacarbazine 1 -
versus ipilimumab alone
nivolumab plus ipilimumab vs. ipilimumab alone 1 -
versus pembrolizumab alone
atezolizumab plus cometinib vs. pembrolizumab alone 1 certainty unassessable-8%