Study explorer (study characteristics and results) method abbreviations pdf   xlsx

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Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID 19 hospitalized meta-analysis

Tolouian bromhexinestandard of careCOVID 19 hospitalizedhigh
59/52 no results
    Ansarin
     
    IRCT202003117046797N
    RCTbromhexinestandard of careCOVID 19 hospitalizedhigh
    39/39 suggested
    • inconclusive 91 % decrease in deaths (PE) but with a low degree of certainty due to high risk of bias
    • suggested 91 % decrease in mechanical ventilation (PE) but with a low degree of certainty due to high risk of bias
    • suggested 86 % decrease in ICU admission (PE) but with a low degree of certainty due to high risk of bias

    COVID-19 mild to moderate meta-analysis

    Li T
     
    NCT04273763
    RCTbromhexinestandard of careCOVID-19 mild to moderatesome concern
    12/6 suggested
    • inconclusive 52 % decrease in clinical deterioration (PE) with a moderate degree of certainty due to some concern in risk of bias
    • suggested 9.0-fold increase in hospital discharge with a moderate degree of certainty due to some concern in risk of bias

    PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
    Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).