nitazoxanide for COVID-19: living meta-analysis of clinical studies

Study explorer (study characteristics and results) method abbreviations pdf xlsx

display ongoing studies
Study	Ref.	Design	studied treatment	control treatment	patients	study risk of bias	sample sizes	Results
COVID-19 mild to moderate meta-analysis
Fontanesi NCT04348409		RCT	nitazoxanide	placebo	COVID-19 mild to moderate	NA	25/25	no results
Silva NCT04463264		RCT	nitazoxanide	placebo	COVID-19 mild to moderate	high	33/13	inconclusive
Rocco NCT04552483		RCT	nitazoxanide	placebo	COVID-19 mild to moderate	high	238/237	inconclusive	inconclusive 19 % decrease in clinical improvement,clinical improvement (7-day) (PE) but with a low degree of certainty due to high risk of bias

PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

Study explorer (study characteristics and results) method abbreviations pdf xlsx

COVID-19 mild to moderate meta-analysis