Study explorer (study characteristics and results) method abbreviations pdf   xlsx

display ongoing studies
Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID-19 severe or critically meta-analysis

COLCHIVID
  NCT04367168		 RCTcolchicineplaceboCOVID-19 severe or criticallyNA
66/60 inconclusive
  • inconclusive 17 % decrease in death or transfer to ICU (PE)
Shi
  NCT04288102		 RCTstem cellsplaceboCOVID-19 severe or criticallysome concern
66/35 inconclusive
    Shu
          ChiCTR2000031494    		 RCTstem cellsstandard of careCOVID-19 severe or criticallysome concern
    		12/29 suggested
    • inconclusive 73 % decrease in clinical deterioration (PE) with a moderate degree of certainty due to some concern in risk of bias
    • suggested 9.3-fold increase in clinical improvement,clinical improvement (14-day) with a moderate degree of certainty due to some concern in risk of bias
    • suggested 5.7-fold increase in clinical improvement (7-day) with a moderate degree of certainty due to some concern in risk of bias
    1 study excluded by filtering options (0 RCT / 1 OBS)

    PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
    Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

     

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