Study explorer (study characteristics and results) method abbreviations pdf   xlsx

display ongoing studies
Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results deaths Eclinical improvement Edeath or ventilation E

COVID 19 hospitalized meta-analysis

Ranjbar
  IRCT20200204046369N1		 RCTmethylprednisolonedexamethasoneCOVID 19 hospitalizedsome concern
44/42 suggested -54%
GLUCOCOVID
  2020-001934- 37		 RCTcorticosteroidscontrolCOVID 19 hospitalizedhigh
35/29 inconclusive
GLUCOCOVID
  2020-001934- 37		 RCTcorticosteroidsstandard of careCOVID 19 hospitalizedhigh
35/29 inconclusive -33%
Metcovid
  NCT04343729		 RCTmethylprednisoloneplaceboCOVID 19 hospitalizedsome concern
209/207 inconclusive -7%
RECOVERY dexamethasone
  NCT04381936		 RCTdexamethasonestandard of careCOVID 19 hospitalizedsome concern
2104/4321 conclusif demonstrated-15% -7%
Tang X
  NCT04273321		 RCTmethylprednisoloneplaceboCOVID 19 hospitalizedsome concern
43/43 suggested -2% 4%

COVID-19 severe or critically meta-analysis

Jamaati
  IRCT20151227025726N1		 RCTdexamethasonestandard of careCOVID-19 severe or criticallysome concern
25/25 suggested 17%
Munch (COVID-STEROID)
  NCT04348305		 RCTHydrocortisoneplaceboCOVID-19 severe or criticallylow
16/14 no results
Rashad
  NCT04519385		 RCTdexamethasonetocilizumab COVID-19 severe or criticallyhigh
75/74 suggested -49%
CAPE-COVID
  NCT02517489		 RCTHydrocortisoneplaceboCOVID-19 severe or criticallylow
76/73 inconclusive -50% -26%
CODEX (Tomazini)
  NCT04327401		 RCTdexamethasonestandard of careCOVID-19 severe or criticallysome concern
151/148 inconclusive -3%
DEXA-COVID19
  NCT04325061		 RCTdexamethasonestandard of careCOVID-19 severe or criticallylow
7/12 inconclusive 90%
Edalatifard
  IRCT20200404046947N1		 RCTmethylprednisolonestandard of careCOVID-19 severe or criticallyhigh
34/34 suggested -64% 990%
REMAP-CAP, fixed 7-day course
  NCT02735707		 RCTHydrocortisonestandard of careCOVID-19 severe or criticallyhigh
143/108 safety concern -5% 39% 157%
REMAP-CAP, shock-dependent course
  NCT02735707		 RCTcorticosteroidsstandard of careCOVID-19 severe or criticallyhigh
152/108 inconclusive -2% 20% 22%
Steroids-SARI
  NCT04244591		 RCTmethylprednisolonestandard of careCOVID-19 severe or criticallysome concern
24/23 inconclusive -8%
4 studies excluded by filtering options (0 RCT / 4 OBS)

PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

 

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