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COVID 19 hospitalized meta-analysis

GRECCO-19, 2020
  NCT04326790		 RCTcolchicinestandard of careCOVID 19 hospitalizedsome concern
55/50 suggested
  • suggested 89 % decrease in clinical deterioration with a moderate degree of certainty due to some concern in risk of bias
Salehzadeh, 2020
  IRCT20200418047126N1		 RCTcolchicineplaceboCOVID 19 hospitalizedsome concern
50/50 inconclusive
    Comparing two groups showed significantly different only in the duration of hospitalized (P<0.05). Although in colchicine group dyspnea was improved more rapid than the placebo group, but it was not meaningful.

    COVID-19 mild to moderate meta-analysis

    Lopes MIF, 2020
          RBR-8jyhxh    		 RCTcolchicineplaceboCOVID-19 mild to moderatehigh
    		17/18 no results

      PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
      Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

       

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