Study explorer (study characteristics and results) method abbreviations pdf   xlsx

display ongoing studies
Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID-19 severe or critically meta-analysis

Lescure (Sarilumab 200mg)
 
NCT04327388
RCTsarilumab low dose (200mg)placeboCOVID-19 severe or criticallysome concern
161/86 inconclusive
  • inconclusive 3 % increase in clinical improvement,clinical improvement (time to event analysis only) (PE) with a moderate degree of certainty due to some concern in risk of bias
Lescure (Sarilumab 400mg)
 
NCT04327388
RCTsarilumabplaceboCOVID-19 severe or criticallysome concern
173/86 inconclusive
    Lescure (Sarilumab 400mg)
     
    NCT04327388
    RCTsarilumab high dose (400mg)placeboCOVID-19 severe or criticallysome concern
    173/86 inconclusive
      2 studies excluded by filtering options (1 RCT / 1 OBS)

      PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
      Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).